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文献和实验Evaluation of the Cardiac Isoform of 2-Macroglobulin as a Factor Inducing Cardiac Hypertrophy
is a cardiac isoform of α2 -macroglobulin belonging to the macro-globulin family. Furthermore, it has been demonstrated that direct injection of the purified 182-kDa protein intravenously (through the tail vein) into the normal animals led to the development
Generation of Antibodies That Are Externally Acting Isoform-Specific Inhibitors of Ion Channels
There is demand for isoform-specific ion channel inhibitors as tools to investigate the biology of �endogenous ion channels and validate them as targets in drug discovery programs. There is also hope that such inhibitors
Cytotoxic Tumor Targeting With scFv Antibody-Modified Liposomes
molecules on the liposome surface are maleimides that are linked to phospholipids composing the liposome bilayer membrane. We illustrate the coupling method of a functionalized single-chain antibody fragment with binding specificity to ED-B fibronectin
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