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LIF,Human,Recombinant

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  • ¥1380 - 27980
  • 普诺赛
  • PCK074
  • 国产
  • 2025年07月30日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现货

    • 供应商

      上海经科化学科技有限公司

    • 规格

      10μg/50μg/500μg/1mg

    规格:10μg产品价格:¥1380.0
    规格:50μg产品价格:¥3680.0
    规格:500μg产品价格:¥17980.0
    规格:1mg产品价格:¥27980.0

    产品信息

    别名 Differentiation-stimulating factor, D factor, Melanoma-derived LPL inhibitor (MLP_x0002_LI), Interleukin 6 family cytokine
    物种 Human
    表达宿主 E.coli
    序列信息 SPLPITPVNATCAIRHPCHNNLMNQIRSQLAQLNGSANALFILYYTAQGEPFPNNLDKLCGPNVTDFPPFHANGTEKAKLVELYRIVVYLGTSLGNITRDQKILNPSALSLHSKLNATADILRGLLSNVLCRLCSKYHVGHVDVTYGPDTSGKDVFQKKKLGCQLLGKYKQIIAVLAQAF with polyhistidine tag at the N-terminus.
    检索号 P15018.1
    分子量 20.52 kDa
    表观分子量 18 kDa
    标签 His-tag at the N-terminus
    生物活性 Measure by its ability to induce TF-1 cells proliferation. The ED50 for this effect is <0.2 ng/mL.

    产品特性

    纯度 >98% as determined by SDS-PAGE. Ni-NTA chromatography
    内毒素 <0.1 EU per 1 μg of the protein by the LAL method.
    保存 Lyophilized protein should be stored at -5~-20°C for 1 year. Upon reconstitution,store at 2-8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g.0.1% BSA,10%FBS,5%HSA or 5% trehalose solution), protein aliquots should be stored at -5~-20°C or -80°C for 3-6 months.
    运输 Ambient temperature or ice pack.
    制剂 The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 7.4.
    复融 It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL.Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.

    背景介绍

    LIF, a pleiotrophic factor, is identified in multiple cell types, including T cells, myelomonocytic lineages, fibroblasts, liver, heart and melanoma. LIF is capable of promoting long-term maintenance of embryonic stem cells by inhibiting spontaneous differentiation. In addition, LIF also have abilities including stimulation of differentiation of cholinergic nerves, the stimulation of acute phase protein synthesis by hepatocytes, and suppression of adipogenesis by supressing the lipoprotein lipase in adipocytes.

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