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IL-5 (C-6His), Human, Recombin

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  • ¥1780 - 27980
  • 普诺赛
  • PCK201
  • 国产
  • 2025年07月30日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 库存

      现货

    • 供应商

      上海经科化学科技有限公司

    • 规格

      500μg/10μg/50μg/1mg

    规格:500μg产品价格:¥17480.0
    规格:10μg产品价格:¥1780.0
    规格:50μg产品价格:¥4980.0
    规格:1mg产品价格:¥27980.0

    产品信息

    别名 Interleukin-5; IL-5; B-cell differentiation factor I; Eosinophil differentiation factor; T-cell replacing factor; TRF; IL5
    物种 Human
    表达宿主 Human Cells
    序列信息  Ile20-Ser134
    检索号 P05113
    分子量 14.2 kDa
    表观分子量 20 kDa
    标签 C-6His
    生物活性 Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells.The ED50 for this effect is 0.1-0.5 ng/ml.

    产品特性

    纯度 >95% as determined by reducing SDS-PAGE.
    内毒素 < 1.0 EU per µg as determined by LAL test.
    保存 Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
    运输 Ambient temperature or ice pack.
    制剂 Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
    复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    背景介绍

    IL-5 is expressed in eosinophils, NK cells, TC2 CD8+ T cells, mast cells, CD45+ CD4+ T cells, gamma delta T cells and IL-1 beta activated endothelial cells. IL-5 acts as a growth and differentiation factor for both B cells and eosinophils. Relative to B cells, IL-5 appears to induce the differentiation of activated conventional B-2 cells into Ig-secreting cells. In addition, it induces the growth of B-1 progenitors as well as IgM production by B-1 cells.IL-5 appears to perform a number of functions on eosinophils. These include the down modulation of Mac-1,the upregulation of Receptors for IgA and IgG,the stimulation of lipid mediator (leukotriene C4 and PAF) secretion and the induction of granule release.IL-5 also promotes the growth and differentiation of eosinophils.

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    IL-5 (C-6His), Human, Recombinant
    ¥1780 - 27980