IL-2RB/ CD122 (C-6His), Human,

Human IL-2RB, also known asInterleukin-2 Receptor subunit beta,is the Receptor for Interleukin-2. IL2 Receptor complex is involved in Receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 Receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane Protein,and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for Receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family Protein tyrosine kinase although it lacks apparent catalytic Motifs.