Mouse Monoclonal Antibody to CD59

Mouse Monoclonal Antibody to C

D59
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  • ¥1280 - 2180
  • Tanda
  • 中国
  • TD-30428
  • 2025年11月13日
  • FCM、ELISA、IHC、ICC
  • Mouse
  • Human
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  • 企业认证

    • 详细信息
    • 技术资料
    • 免疫原

      peptide

    • 亚型

      IgG1

    • 形态

      Liquid

    • 保存条件

      -20℃

    • 克隆性

      mAb

    • 适应物种

      Human

    • 保质期

      1年

    • 目录编号

      TD-30428

    • 级别

      科研级

    • 库存

      88

    • 供应商

      武汉天德

    • 宿主

      Mouse

    • 应用范围

      FCM、ELISA、IHC、ICC

    • 靶点

      详询

    • 抗体英文名

      Mouse Monoclonal Antibody to CD59

    • 抗体名

      CD59

    • 规格

      100ul/50ul

    规格:100ul产品价格:¥2180.0
    规格:50ul产品价格:¥1280.0

    Mouse Monoclonal Antibody to CD59

    Description

    This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

    Specification

    Aliases1F5; EJ16; EJ30; EL32; G344; MIN1; MIN2; MIN3; MIRL; HRF20; MACIF; MEM43; MIC11; MSK21; 16.3A5; HRF-20; MAC-IP; p18-20
    Entrez GeneID966
    SwissprotP13987
    clone8D2B8
    WB Predicted band size14.2kDa
    Host/IsotypeMouse IgG1
    Antibody TypePrimary antibody
    StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
    Species ReactivityHuman
    ImmunogenPurified recombinant fragment of human CD59 (AA: 31-111) expressed in E. Coli.
    FormulationPurified antibody in PBS with 0.05% sodium azide

    Application

    IHC1/200 - 1/1000
    ICC1/50 - 1/200
    FCM1/200 - 1/400
    ELISA1/10000

    Product Image

    Mouse Monoclonal Antibody to C
    Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng
    • Mouse Monoclonal Antibody to C
      Immunofluorescence analysis of MCF-7 cells using CD59 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
    • Mouse Monoclonal Antibody to C
      Immunofluorescence analysis of Hela cells using CD59 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
    • Mouse Monoclonal Antibody to C
      Flow cytometric analysis of HeLa cells using CD59 mouse mAb (green) and negative control (red).
    • Mouse Monoclonal Antibody to C
      Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using CD59 mouse mAb with DAB staining.
    • Mouse Monoclonal Antibody to C
      Immunohistochemical analysis of paraffin-embedded human esophageal cancer tissues using CD59 mouse mAb with DAB staining.

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