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Mouse Monoclonal Antibody to C

D45
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  • ¥1280 - 2180
  • Tanda
  • 中国
  • TD-20298
  • 2026年04月06日
  • ELISA、IHC
  • Mouse
  • Human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      peptide

    • 亚型

      IgG1

    • 形态

      Liquid

    • 保存条件

      -20℃

    • 克隆性

      mAb

    • 适应物种

      Human

    • 保质期

      1年

    • 目录编号

      TD-20298

    • 级别

      科研级

    • 库存

      88

    • 供应商

      武汉天德

    • 宿主

      Mouse

    • 应用范围

      ELISA、IHC

    • 靶点

      详询

    • 抗体英文名

      Mouse Monoclonal Antibody to CD45

    • 抗体名

      CD45

    • 规格

      100ul/50ul

    规格:100ul产品价格:¥2180.0
    规格:50ul产品价格:¥1280.0

    Mouse Monoclonal Antibody to CD45

    Description

    CD45, also known as TPRC(protein tyrosine phosphatase, receptor type, C). The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.

    Specification

    Aliases LCA; LY5; B220; CD45; T200; CD45R; GP180; PTPRC
    Entrez GeneID 5788
    Swissprot P08575
    clone 4A8A4C7A2
    Host/Isotype Mouse IgG1
    Antibody Type Primary antibody
    Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
    Species Reactivity Human
    Immunogen Purified recombinant fragment of CD45 expressed in E. Coli.
    Formulation Ascitic fluid containing 0.03% sodium azide.

    Application

    IHC 1/200 - 1/1000
    ELISA 1/10000

    Product Image

    • 产品细节图片1
      Immunohistochemical analysis of paraffin-embedded human lymph node tissue,showing membrane and cytoplasmic localization with DAB staining using CD45 mouse mAb.
     

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    图标文献和实验
    相关实验
    • Monoclonal Antibody Production

      and screening of the hybridomas: 1. Bleeding Mice (1) Place the mouse in a mouse restrainer. (2) Sterilize the tail with 70% ethanol. (3) With a razor blade,nip off the last 2 mm of the tip of the tail. (4) Using a milking motion,pull blood down and let

    • Monoclonal Antibody Production Protocol

      complete with MCM instead of PCM (= IMDM - m ), and keep it in the incubator for fused cells. Isolation of spleen cells Sacrifice mouse by cervical dislocation. Immerse mouse in 70% Ethanol. Remove spleen ( on the left side ) and transfer into a small

    • monoclonal antibody production fusion

        Fusion is an important procedure to produce monoclonal antibodies (MoAb). PROTOCOL   prepare the culture of myeloma cells and maintain the concentration of the cells at the level of less than 10

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