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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
4°C, stored under nitrogen
- 英文名:
GS 4071-<sup>13</sup>C,d<sub>3</sub>; Ro 64-0802-<sup>13</sup>C,d<sub>3</sub>; Oseltamivir carboxylate-<sup>13</sup>C,d<sub>3</sub>
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- 规格:
1 mg
产品活性:Oseltamivir acid-13C,d3 (GS 4071-13C,d3; Ro 64-0802-13C,d3) 是 13C 和氘标记的 Oseltamivir acid (HY-13318)。Oseltamivir acid 是 Oseltamivir phosphate 的活性代谢产物, 可抑制流感病毒神经氨酸酶 (IC50=2 nM)。Oseltamivir acid 具有口服活性,可用于研究流感病毒 A/B 的感染。
产品来源: www.medchemexpress.cn/oseltamivir-acid-13c-d3.html
研究领域:Others | Anti-infection | Metabolic Enzyme/Protease
作用靶点:Isotope-Labeled Compounds | Influenza Virus | Drug Metabolite
In Vitro: Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
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Quantitation of Methylmalonic Acid in Plasma Using Liquid Chromatography Tandem Mass Spectrometry
Methylmalonic acid (MMA), a biochemical marker for vitamin B12 deficiency, is commonly measured in serum and urine using liquid chromatography-tandem mass spectrometry (LC-MS-MS) with electrospray ionization. Improvements in sample
Accelerated Molecular Dynamics in Computational Drug Design
emphasis is placed on the use of these methods in computer-aided drug design, and the example of oseltamivir binding to neuraminidase is highlighted for both cases.
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