- ￥0
- Biorbyt
- 英国
- orb1942577
- 2026年08月07日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
相关阅读
AJE 润色服务限时 8 折起，权威机构信任 15+ 年Cytoscape 教程来了！快速实现顶刊同款通路网络图五大应用案例：Mustang Q 膜层析应用全解析1 个小工具，一次性搞定流程图、质粒图谱和信号通路图- 详细信息
- 技术资料
- 保存条件：
详询
- 保质期：
12 months from date of receipt.
- 英文名：
HMGB1-IN-2
- 库存：
99
- 供应商：
Biorbyt
- 规格：
5 mg/50 mg
| 规格： | 5 mg | 产品价格： | ￥0.0 |
|---|---|---|---|
| 规格： | 50 mg | 产品价格： | ￥0.0 |
类别: Small Molecules
描述: HMGB1-IN-2 is a selective HMGB1 inhibitor that at 30 µM reduces IL-1β, TNF-α, and caspase-1 p20 while inhibiting NF-κB phosphorylation in vitro, and at 15 mg/kg i.p. alleviates septic acute kidney injury in mice. It also inhibits Huh7 and A549 cells with IC50 values of 77.0 and 82.0 µM, supporting research in inflammation, sepsis, and cancer.
靶点: Others,NF-κB,Apoptosis,Caspase,Interleukin
分子式: C53H71N3O11
分子量: 926.14
SMILES: COc1ccc(/C=C/C(O[C@H]2CC[C@]3(C(C2(C)C)CC[C@@]4([C@@H]3C(C=C5C6C[C@@](C(OCC7=NN(C8OC(C)C(OC(C)=O)C(OC(C)=O)C8)N=C7)=O)(CC[C@@]6(CC[C@]54C)C)C)=O)C)C)=O)cc1
研究领域: Cell Biology, Immunology & Inflammation, Protein Biochemistry, Signal Transduction
保存条件: -20°C
备注: For research use only.
描述: HMGB1-IN-2 is a selective HMGB1 inhibitor that at 30 µM reduces IL-1β, TNF-α, and caspase-1 p20 while inhibiting NF-κB phosphorylation in vitro, and at 15 mg/kg i.p. alleviates septic acute kidney injury in mice. It also inhibits Huh7 and A549 cells with IC50 values of 77.0 and 82.0 µM, supporting research in inflammation, sepsis, and cancer.
靶点: Others,NF-κB,Apoptosis,Caspase,Interleukin
分子式: C53H71N3O11
分子量: 926.14
SMILES: COc1ccc(/C=C/C(O[C@H]2CC[C@]3(C(C2(C)C)CC[C@@]4([C@@H]3C(C=C5C6C[C@@](C(OCC7=NN(C8OC(C)C(OC(C)=O)C(OC(C)=O)C8)N=C7)=O)(CC[C@@]6(CC[C@]54C)C)C)=O)C)C)=O)cc1
研究领域: Cell Biology, Immunology & Inflammation, Protein Biochemistry, Signal Transduction
保存条件: -20°C
备注: For research use only.
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
HMGB1-IN-2，orb1942577，Biorbyt
￥0
