- ￥0
- Biorbyt
- 英国
- orb1942055
- 2026年08月07日
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- 文献和实验
- 技术资料
- 保存条件：
详询
- 保质期：
12 months from date of receipt.
- 英文名：
Cisplatin-resistant cells-IN-1
- 库存：
99
- 供应商：
Biorbyt
- 规格：
5 mg/50 mg
| 规格： | 5 mg | 产品价格： | ￥0.0 |
|---|---|---|---|
| 规格： | 50 mg | 产品价格： | ￥0.0 |
描述: Cisplatin-resistant cells-IN-1 (Compound 8) is a potent small molecule active against cisplatin- and tamoxifen-resistant cancer cell lines, demonstrating low nanomolar IC50 values. It is a valuable chemical tool for in vitro studies of multidrug resistance mechanisms and overcoming chemoresistance in oncology research.
靶点: Others
保存条件: -20°C
备注: For research use only.
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文献和实验have been extensively translated to, and validated in, human cells. Strategies, experimental conditions, and methods are presented to enable further study of resistance to cisplatin as well as other important drugs.
Mutagenesis and the Selection of Resistant Mutants
: one challenges a large population of cells with a selective agent, and identifies “survivors” on the basis of their capacity to divide to form cell masses, or organized structures. Thus, the procedures used to select mutants resistant to a range of different
Development of Drug-Resistant Models
as pivotal to the emergence of drug-resistant cells. The hypothesis suggested that a drug-resistant cell emerged from the clonal expansion of spontaneously mutated cells and not from changes in cellular function induced by drugs. The methodology used
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