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- Biorbyt
- 英国
- orb1941752
- 2026年08月07日
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- 文献和实验
- 技术资料
- 保存条件：
详询
- 保质期：
12 months from date of receipt.
- 英文名：
Antiproliferative agent-39
- 库存：
99
- 供应商：
Biorbyt
- CAS号：
871837-61-5
- 规格：
5 mg/50 mg
| 规格： | 5 mg | 产品价格： | ￥0.0 |
|---|---|---|---|
| 规格： | 50 mg | 产品价格： | ￥0.0 |
描述: Antiproliferative Agent-39 (Compound 12) is a broad-spectrum cytostatic compound, demonstrating inhibitory activity against multiple cancer cell lines such as A549, SNU-638, Col2, HT1080, and MCF-7 with IC50 values ranging from 6.3 to 25 μM. This small molecule is a useful research tool for in vitro oncology studies investigating cell proliferation mechanisms.
靶点: Others
分子式: C22H22N4O3
分子量: 390.44
SMILES: O=C1NC=2C=CC(=CC2C1=C3NC=4C=CC=CC4C3=NO)NC(=O)CC(C)(C)C
保存条件: -20°C
备注: For research use only.
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文献和实验One of the more intriguing features of the hemopoietic system is the ability of a single phenotypically homogeneous stem cell to give rise—through differentiation and development—to all the phenotypically diverse mature immuno-hemopoietic
compounds and for the derivation of IC50 values. IC50 value is defined as the concentration of a test compound required to achieve half maximal inhibition of methyl-[3H]-thymidine incorporation, a parameter that is indicative of antiproliferative potency. IC
Functional Analysis of the Antimitogenic Activity of Tumor Suppressors
Loss of tumor suppressors contributes to numerous cancer types. Many, but not all, proteins encoded by tumor suppressor genes have antiproliferative activity and halt cell-cycle progression. In this chapter, we present three methods
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