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- 文献和实验
- 技术资料
- 保存条件:
详询
- 保质期:
12 months from date of receipt.
- 英文名:
RGFP966 (E-isomer)
- 库存:
99
- 供应商:
Biorbyt
- CAS号:
1396841-57-8
- 规格:
5 mg/10 mg/25 mg/50 mg/100 mg
| 规格: | 5 mg | 产品价格: | ¥936.0 |
|---|---|---|---|
| 规格: | 10 mg | 产品价格: | ¥1053.0 |
| 规格: | 25 mg | 产品价格: | ¥1404.0 |
| 规格: | 50 mg | 产品价格: | ¥1872.0 |
| 规格: | 100 mg | 产品价格: | ¥2574.0 |
描述: RGFP966 is a potent and highly selective HDAC3 inhibitor, demonstrating an IC50 of 0.08 μM and over 200-fold selectivity versus other HDAC isoforms. It is widely used in research to investigate epigenetic mechanisms in neurobiology, oncology, and metabolic diseases, with applications in both cellular and animal models.
别名: RGFP 966, RGFP966, RGFP-966, E-isomer, HDAC3
靶点: HDAC
分子式: C21H19FN4O
分子量: 362.4
纯度: 99.10% (May vary between batches)
SMILES: Nc1cc(F)ccc1NC(=O)\C=C\c1cnn(CC=Cc2ccccc2)c1
溶解度: Ethanol:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.52 mM);DMSO:67 mg/mL (184.88 mM);H2O:< 1 mg/mL (insoluble or slightly soluble)
研究领域: Epigenetics & Chromatin, Molecular Biology
保存条件: -20°C
备注: For research use only.
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文献和实验A Homogeneous Assay to Assess GABA Transporter Activity
) GAT uptake buffer (see recipe ) with and without 4× (3.2% v/v) dimethylsulfoxide (DMSO) GAT‐1 inhibitor compounds (see recipe ), e.g., CI‐966 (Tocris) and NO‐711
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for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy. Cell Res 30, 966-979 (2020).9.L. Zhang et al., Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer. Cell 181, 442-459 e429 (2020
CENP-E (1) NM_001813 944-966 aaactcttactgctctccagt Human HeLa
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