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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
- 保质期:
6个月
- 英文名:
Recombinant Human Single Ig IL-1-related receptor (SIGIRR), partial
- 库存:
详询客服
- 供应商:
biorbyt
- 规格:
20 ug
产品别名:Single Ig IL-1R-related molecule;Single immunoglobulin domain-containing IL1R-related protein;Toll/interleukin-1 receptor 8 (TIR8)
应用笔记:We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
纯度:Greater than 90% as determined by SDS-PAGE.
生物来源:Homo sapiens (Human)
蛋白序列:MPGVCDRAPDFLSPSEDQVLRPALGSSVALNCTAWVVSGPHCSLPSVQWLKDGLPLGIGGHYSLHEYSWVKANLSEVLVSSVLGVNVTSTEVYGAFTCSIQNISFSSFTLQRAGPTSH
分子量:14.8 kDa
表达区域:1-118aa
标签:C-terminal 6xHis-tagged
防腐剂:If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
来源:Mammalian cell
形态:Liquid or Lyophilized powder
Uniprot ID:Q6IA17
Note:For research use only.


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文献和实验activation motif; JAK, Janus kinase; NFκB, nuclear factor κB; PKB, protein kinase B; PLC, phospholipase C; SIGIRR, single Ig IL-1-related receptor; sIL-1RAcP, soluble IL-1 receptor accessory protein; sST2, soluble ST2; STAT3, signal transducer and activator
【申请上传】Current Protocols in Immunology
Motifs, and Expression of Nonclassical Class I and Related Genes and Molecules 1N Overview of Protein Folds in the Immune System1 1O Nomenclature of the Human T Cell Receptor Genes 1P Nomenclature of the Human Immunoglobulin Genes 1Q Safe Use
的精细拆解 要深入研究 Siglec,首先必须理解其独特的分子架构。Siglec 属于 I 型跨膜蛋白,是免疫球蛋白超家族(IgSF)的成员。其胞外区由不同数量的 Ig 样结构域组成,最末端(N 端)是一个特征性的 V-set 结构域,这是所有 Siglec 成员识别配体的物理核心。 在 V-set 结构域内部,存在一个高度保守的精氨酸(Arginine)残基。这个残基在空间结构上形成了一个带正电荷的“口袋”,能够与唾液酸分子的羧基形成关键的盐桥。正是这种分子尺度的精密耦合
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