A synthetic peptide from the internal region of ATM which includes the mutation of Q2442P, huma n origin.
亚型:
lgG
形态:
液体
应用范围:
ELISA, WB, IHC
保存条件:
-20℃
浓度:
1mg/ml
规格:
100μl
ATM (Q2442P)
Catalog Number: TD26142 Gene Symbol: ATM Description: Anti-ATM (Q2442P) Mouse Monoclonal Antibody Background: Ataxia telangiectasia mutated (ATM) is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading to cell cycle arrest, DNA repair or apoptosis. Activity of ATM protein is under tight control, and mutation of ATM can cause disease such as Ataxia telangiectasia (AT) and cancers. Immunogen: A synthetic peptide from the internal region of ATM which includes the mutation of Q2442P, huma n origin. Tested applications: ELISA, WB, IHC Recommended dilutions: ELISA: 1:1000-1:5000 WB:1:100-1:1000 IHC:1:50-1:500 Concentration: 1 mg/ml Host: Mouse Clonality: Monoclonal Purity: Purified from ascites Format: Liquid Preservative: no Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol Species Reactivity: Recognizes ATM (Q2442P), but not wild type ATM protein from vertebrates. Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles. Western blot:
Western blot analysis of recombinant ATM (Q2442P) and wildtype proteins. Purified His-tagged ATM (Q2442P) protein (amino acids 2400-3056, lane 2) and corresponding wild type protein (lane 1) were blotted with anti-ATM (Q2442P) mouse monoclonal antibody (Cat. #TD-26142).