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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
储存于-20 ° C
- 保质期:
1年
- 英文名:
immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus]
- 库存:
100
- 供应商:
艾美捷科技
- CAS号:
无
- 规格:
1mg
immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus],immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus],immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus],immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus]
immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus]-immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus]
产品货号:APE-A1072-1
产品规格:1mg
免疫球蛋白轻链片段

Immunology/Inflammation

immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus]-immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus]储存于-20 ° C
点击:immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus]-immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus]查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多APExBIO公司特色小分子抑制剂等产品评论,请点击查看艾美捷特色产品中心。
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文献和实验PCR Cloning of Human Immunoglobulin Genes
One of the first steps in an antibody-engineering project is the isolation of the immunoglobulin heavy (VH )- and light (VL )-chain variable-region genes that encode the binding domains of an antibody. This is best accomplished using
=crystallizable fragment)的性质而异。 L链有 K链和λ链,分子量均约为 22, 000。无论哪种类型都有具κ链和具λ链的,一个分子各有其中一方的两条,没有双方同时具备的。人的 lgG分子约 60%为κ型,约 40%为λ型(参照附表)。根据骨髓瘤蛋白质的氨基酸排列的研究,一般认为, L链及 H链从 N末端起约 110个氨基酸( L链的约 1/2长度)的排列,是按照抗原待异性而有部分差异的排列方式进行的。这部分称为可变区( variable region),可以认为, L链及 H链双方的可变区参与
8 The Recovery of Immunoglobulin Sequences from Single Human B Cells by Clonal Expansion
chain reaction (PCR) amplification of their variable-region genes, thereby immortalizing the VH and VL regions from individual human B cells. The method relies on the clonal expansion of single B cells in which cell-cell interactions (CD40-CD
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