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- 详细信息
- 文献和实验
- 技术资料
- 英文名:
/
- 库存:
现货库存
- 供应商:
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- 肿瘤类型:
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- 细胞类型:
/
- 品系:
/
- 组织来源:
ATCC/DSMZ/ECACC
- 相关疾病:
/
- 物种来源:
人或动物
- 免疫类型:
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- 细胞形态:
/
- 是否是肿瘤细胞:
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- 器官来源:
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- 运输方式:
常温或干冰
- 年限:
/
- 生长状态:
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- 规格:
T25
| 种属 | 兔 |
| 组织来源 | 脑动脉组织 |
| 传代比例 | 1:2传代 |
| 完全培养基配置 | 基础培养基500ml ;生长添加剂5ml ;胎牛血清25ml ;双抗5ml |
| 简介 | 脑微血管内皮细胞是血脑屏障的主要组成成分 ,能够限制可溶性物质和细胞等从血液进入大脑。大脑微血管内皮细胞 与外周内皮细胞相比具有一些相同特性 ,脑微血管内皮细胞存在许多细胞间紧密连接 ,产生很高的跨内皮阻抗 ,延迟 细胞旁的通量;脑微血管的内皮细胞间衔接得十分紧密 ,不象其他组织的血管内皮细胞那样有较大的缝隙脑微血管内 皮细胞缺乏内皮细胞的窗孔结构 ,其液相物质胞饮水平较低;脑微血管内皮细胞具有不对称定位酶和载体介导转运系 统 ,从而产生 “两极分化”的表现型。 与外周内皮细胞相同 ,大脑微血管内皮细胞表面表达细胞粘附分子 ,调控白 细胞进入大脑。由于微血管内皮细胞的器官特异性 ,内皮细胞通常取源于疾病研究的相关组织。 |
| 形态 | 铺路石状细胞样 ,不规则细胞样 |
| 细胞检测 | 血管假性血友病因子( vWF )免疫荧光染色为阳性免疫荧光鉴定 ,细胞纯度可达90%以上 ,不含有HIV-1、HBV、 HCV、支原体、细菌、酵母和真菌等。 |
patients even though it inhibited osteoclast resorptive activity. Thus, other cells in addition to osteoclasts are likely involved in modulating tumor growth in the bone. The immune system has the ability to eliminate tumor cells. Nevertheless, tumor cells can acquire the ability to escape immune control. Our recent observations indicated that a decline in the ability of the immune cells to recognize and kill the tumor drives tumor dissemination to bone even when osteoclasts are inhibited by potent antiresorptive agents. This review focuses on the antitumor and protumor effects of various immune cell populations involved in the bone metastatic process. We also discuss strategies to enhance antitumor immune responses and bypass cancer immune resistance.
2001, 20(5): 377~379.reveal increased immune transcripts in cancer cells. Cells gradually acquire immune transcripts in malignant transformation. Notably, cancer cell-derived immune transcripts contribute to distinct
providing an example of cancer cell plasticity and a refined view of tumor microenvironpknt.Altered glycosylations, which are associated with expression and activities of glycosyltransferases,
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文献和实验/Li S J, and Li J M. Research Progress on Losses ofFeryilizer Nitrogen[J]. Agro-environmental Protection,
2001, 20(5): 377~379.
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