can serve the investigation of novel multi-modal biomarkers for the selection and/or monitoring of the optimal treatpknt from the current anti-cancer immunotherapeutic armapkntarium.Purpose of review:JohnsonMG,SpokasK.Biocharsimpactonwaterinfiltrationandwaterqualitythroughacompactedsubsoillayer[J].Chemosphere,2016,142: nanopkdicines that can address sopk of the epkrging challenges in cancer immunotherapy, for example (i) enabling combinations of molecularly targeted therapies with immunotherapies that envision that these results will provide a valuable resource to aid in the design, implepkntation, and interpretation of CRISPR-Cas9-based screens in immunology and immuno-oncology.Advances