nitrogen contentin stems,leavesandrootsincreasedby26.37%and48.38%,respectively,andthenitrogenutilization eff iciency reached 46.69%, which increased by19.01% compared to nitrogen fertilizer onlyandby 4.85% comparedtotheapplicationof Here, we propose two broad approaches to convert cold tumors into hot tumors. The first is to induce immunogenic tumor cell death, through the use of oncolytic viruses or bacteria,