人淋巴管内皮细胞

  Cai J，Yuan H，Wang Q，et al．HMGB1 －Driven Inflammation and In- timal Hyperplasia After Arterial Injury Involves Cell －Specific Actions  Mediated by  TLR4［J］． Arterioscler  Thromb  Vasc   Biol ，2015 ，35  ( 12) :  2579－2593 .
［10］ Lei C，Wu B，Cao T，et al．Activation of the high－mobility group box   multiple sites of metastasis or sites of potential toxicity. To address this need, in vivo imaging of both adaptive and innate immune cell populations has emerged as a tool to quantify spatial leukocyte accumulation in tumors non-invasively. Here we review recent progress in the translational development of probes for in vivo leukocyte imaging, focusing on complementary

Malignant urological tumours account for a relevant number of patients who develop bone metastasis throughout the course of their disease. Diagnosis of bone metastasis is mostly achieved by imaging studies including plain X-ray, computed tomography or magnetic resonance tomography. Differential diagnosis between benign and malignant processes in the bone can be sometimes challenging so that minimally or open operative biopsy of the bone becomes necessary in rare cases. After diagnosis of bone metastasis medical treatment using bisphosphonates or denosumab should be initiated in order to prevent skeletal complications. Therapeutic goals for symptomatic bone metastasis are the reduction of tumour associated pain and stabilization of the bone. Pathologic fractures are mostly being treated using either minimally invasive or open operative techniques for stabilizing the segment of the bone or spine. In case of accompanying neurologic symptoms immediate intervention and decompression of the neural structures is warranted in order to prevent irreversible neurologic deficits.