- ￥1380 - 3300
- Elabscience
- E-AB-70261
- 武汉
- 2026年09月24日
- IHC
- Rabbit
- Human;Mouse;Rat
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- 文献和实验
- 技术资料
- 抗体名：
Mineralocorticoid receptor Polyclonal Antibody_货号:E-AB-70261_多克隆抗体
- 抗体英文名：
Mineralocorticoid receptor Polyclonal Antibody
- 靶点：
Mineralocorticoid receptor
- 浓度：
5 μL/Test
- 应用范围：
IHC
- 宿主：
Rabbit
- 适应物种：
Human;Mouse;Rat
- 保质期：
12个月
- 级别：
科研
- 库存：
99
- 供应商：
武汉伊莱瑞特生物科技股份有限公司
- 标记物：
Unconjugated
- 克隆性：
Polyclonal
- 保存条件：
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
- 形态：
液体
- 亚型：
IgG
- 规格：
200μL/120μL/60μL
| 规格： | 200μL | 产品价格： | ￥3300.0 |
|---|---|---|---|
| 规格： | 120μL | 产品价格： | ￥2220.0 |
| 规格： | 60μL | 产品价格： | ￥1380.0 |
货号：E-AB-70261
| Verified Samples |
Verified Samples in IHC:Human stomach,Mouse kidney,Rat kidney
|
| Dilution |
IHC 1:200-1:800
|
| Clonality |
Polyclonal
|
| Isotype |
IgG
|
| Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse Mineralocorticoid receptor
|
| Abbre |
Mineralocorticoid receptor
|
| Synonyms |
Aldosterone receptor;MCR;MGC133092;Mineralocorticoid receptor;MLR;MR;NR3 C2;NR3C2;NR3C2 protein;Nuclear receptor subfamily 3 group C member 2抗体
|
| Swissprot |
P08235,Q8VII8,P22199
|
| Cellular Localization |
Cytoplasm, Endoplasmic reticulum, Membrane, Nucleus
|
| Concentration |
1.3 mg/mL
|
| Storage |
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
|
| Buffer |
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
|
| Purification Method |
Affinity purification
|
| Research Areas |
Signal Transduction;Cardiovascular;Epigenetics and Nuclear Signaling
|
| Conjugation |
Unconjugated
|
| Background |
This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.
|
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文献和实验L-arginine and lisinopril supplementation protects against sodium fluoride–induced nephrotoxicity and hypertension by suppressing mineralocorticoid receptor and angiotensin-converting enzyme 3 activity
IF:5.19
Journal:ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
DOI:10.1007/s11356-022-23784-1
Construction of Polyclonal Antibody Libraries Using Phage Display
Polyclonal antibody libraries (PCALs) are standardized mixtures of antibodies (Abs) specific for an antigen (Ag) or multi-Ag target (a poly-Ag). As the immunoglobulin (Ig) genes are cloned, the mixtures can be perpetuated, amplified
Preparation of Polyclonal Antibodies to Retinoid Receptors
of a retinoid “X” receptor α (RXRα) antibody on Western blots contributed to the identification of the RXR ligand by detection of the receptor in fractions of whole-cell lysates that were able to bind the 9-cis retinoic acid ligand (2 ) Antibodies
Cotransfection Assays and Steroid Receptor Biology
The glucocorticoid, mineralocorticoid, progesterone, androgen, estrogen α and estrogen β receptors (GR, MR, PR, AR, ERα, and ERβ, respectively) form the steroid receptor family, part of the nuclear receptor superfamily
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