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- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
TGF β Receptor I Polyclonal Antibody_货号:E-AB-16094_多克隆抗体
- 抗体英文名:
TGF β Receptor I Polyclonal Antibody
- 应用范围:
IHC;ELISA
- 宿主:
Rabbit
- 适应物种:
Human;Mouse;Rat
- 保质期:
12个月
- 目录编号:
E-AB-16094
- 级别:
科研级别
- 库存:
999
- 供应商:
武汉伊莱瑞特生物科技股份有限公司
- 标记物:
Unconjugated
- 克隆性:
Polyclonal
- 保存条件:
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
- 形态:
液体
- 亚型:
IgG
- 规格:
200μL/120μL/60μL/20μL
| 规格: | 200μL | 产品价格: | ¥2365.0 |
|---|---|---|---|
| 规格: | 120μL | 产品价格: | ¥1640.0 |
| 规格: | 60μL | 产品价格: | ¥1010.0 |
| 规格: | 20μL | 产品价格: | ¥420.0 |
货号:E-AB-16094
| Verified Samples |
Verified Samples in IHC:Human gastric cancer
|
| Dilution |
IHC 1:100-1:300
|
| Clonality |
Polyclonal
|
| Isotype |
IgG
|
| Immunogen |
Synthetic peptide of human TGFBR1
|
| Abbre |
TGFBR1
|
| Synonyms |
AAT 5;AAT5;Activin A receptor type II like kinase 53kDa;Activin A receptor type II like kinase;53kD;Activin A receptor type II like protein kinase of 53kD;activin A receptor type II-like kinase;53kDa;activin A receptor type II-like protein kinase of 53kD;Activin receptor like kinase 5;Activin receptor-like kinase 5;ACVRLK 4;ACVRLK4;ALK 5;ALK-5;ALK5;LDS1A;LDS2A;MSSE;Serine/threonine protein kinase receptor R4;Serine/threonine-protein kinase receptor R4;SKR 4;SKR4;TbetaR I;TbetaR-I;TGF beta receptor type 1;TGF beta receptor type I;TGF beta type I receptor;TGF-beta receptor type I;TGF-beta receptor type-1;TGF-beta type I receptor;TGFBR 1;TGFBR1;TGFBR1 protein;TGFR 1;TGFR-1;TGFR1;TGFR1;Transforming growth factor beta receptor 1;Transforming growth factor beta receptor I (activin A receptor type II like kinase;53kD);Transforming growth factor beta receptor I;transforming growth factor;beta receptor 1;transforming growth factor;beta receptor I (activin A receptor type II-like kinase;53kD);Transforming growth factor-beta receptor type I抗体
|
| Swissprot |
P36897
|
| Cellular Localization |
Cytoplasm
|
| Concentration |
0.3 mg/mL
|
| Storage |
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
|
| Buffer |
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
|
| Purification Method |
Affinity purification
|
| Research Areas |
Cancer; Cardiovascular; Metabolism; Signal Transduction; Stem Cells
|
| Conjugation |
Unconjugated
|
| Background |
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.
|
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文献和实验自2012年第一篇引用文献问世,至2023年8月,Elabscience已协助各地科研工作者发表超13,000篇SCI文献,包括行业顶/级期刊Nature Medicine, Nature, Cell, Signal Transduction and Targeted Therapy, Circulation, Molecular Cancer, Immunity, Advanced Materials等,总影响因子(IF)59472.59,其中IF≥30的文献超30篇,最高影响因子为66.849,发文单位包含北京大学、中国科学技术大学、浙江大学、斯坦福大学、耶鲁大学、柏林夏里特大学等国内外各大高校。
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11 Detection of TGF Type II Receptor Hotspot Mutations: The BAT-RII Assay
The transforming growth factor-β (TGF-β) pathway is important in the growth control of many different cell types, particularly epithelial cells, and is often disrupted in the development of cancer (1 ,2 ). The most common mutation
Measurements of Active TGF Generated by Culture Cells
The transforming growth factors-β (TGF-βs) constitute a family of potent regulators of cellular differentiation, proliferation, migration, and protein expression (1 ,2 ). Three isoforms of TGF-β have been described in mammals: TGF
Characterization of SMAD Phosphorylation and SMAD/Receptor Interaction
Signaling by transforming growth factor-(β superfamily members is initiated when ligand binds to and induces formation of a heteromeric receptor complex composed of type I and type II serine/threonine kinase receptors (reviewed in refs. 1 –
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