DUAL LOCK RETAINING RING, JA16

Single and Dual Birthdating Procedures for Assessing the Response of Adult Neural Stem Cells to the Infusion of a Soluble Factor Using Halogenated Thy

is the most basic procedure to study the effects of a soluble factor on aNSC proliferation. We also describe a dual replication labeling protocol using two different halogenated thymidine analogs, chloro? and iododeoxyuridine (CldU and IdU), that allows tracking

Amicon Stirred Ultrafiltration Cells

. If cap assembly does not slide easily, lubricate O-ring lightly with petroleum jelly. Do not allow petroleum jelly to contact membrane! Set pressure-relief valve to horizontal (open) position. Slide cell into retaining stand, fitting ring

AI 筛选 + 虚拟筛选：新药研发的 “双引擎” 的核心逻辑

) 和 MPR (检测离子通道活性) 双实验，筛选出 2 个双活性化合物 (IC50 分别为 1.88μM、6.82μM) 。进一步合成 10 个结构类似物开展 SAR 分析，发现类似物 2g (R2/R3 为For fluorobenzene ring) 活性最优 (IC50=1.31μM) ，分子对接显示其通过额外氢键增强与 Asp92、Lys297 的结合，为后续优化提供明确方向。   想让虚拟筛选又快又准？关键是“按需选择，合理组合