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- 2025年12月05日
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Deac-SS-Biotin
MCE 国际站：Deac-SS-Biotin
产品活性：Deac-SS-Biotin 是一种有效的抗癌剂。Deac-SS-Biotin 通过生物素介导的内吞作用摄取进入细胞。Deac-SS-Biotin 与 DTT (谷胱甘肽) 结合可有效抑制微管组装并显示出更强的抗肿瘤活性。
研究领域：Others
作用靶点：Others
In Vitro: Deac-SS-Biotin (compound 9) (5 µM; 24 h) has a remarkable reduction-responsive drug release.
Biotin effectively preventes Deac-SS-Biotin from binding to biotin receptor, thereby blocking the cellular uptake of Deac-SS-Biotin.
Deac-SS-Biotin (5 µM, 5 µM and 10 µM DTT; 0-80 min) effectively inhibits microtubule assembly and displays greater antitumor activity.
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文献和实验reagent (Sulfo-NHS-SS-Biotin) to label exposed primary amines of proteins on the surface of intact adherent or suspension cells. Treated cells are then harvested and lysed, and the labeled surface proteins are affinity-purified using Thermo Scientific
(Molecular Genetics Network Lab) ・ 5'-end Labeling (Amersham Pharmacia) ・ Fill in Labeling of DNA (Mike A. Dyer) ・ 5'-End Labeling (Fermentas) T4 polynucleotide kinase labeling (ds and ss DNA or RNA
Synchronizing Protein Transport in the Secretory Pathway
RUSH plasmid coding for the protein of interest as a reporter (see protocol 1 ) Biotin, 4 mM stock solution (see recipe
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