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- ProSci
- 美国
- PSI-98-850-0.1mg
- 2025年07月11日
- Flow
- 大鼠
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Activated 5C2 cells
- 保存条件：
Store vial at 2-8℃
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
大鼠
- 应用范围：
Flow
- 抗体英文名：
CD80 Antibody [1G10] (PE-Cy5)
- 抗体名：
CD80 Antibody [1G10] (PE-Cy5)
- 规格：
0.1mg
CD80 抗体 [1G10] (PE-Cy5)，CD80 Antibody [1G10] (PE-Cy5)，CD80 抗体 [1G10] (PE-Cy5),CD80 Antibody [1G10] (PE-Cy5)
产品名称：CD80 抗体 [1G10] (PE-Cy5)-CD80 Antibody [1G10] (PE-Cy5)
产品货号：PSI-98-850-0.1mg
产品规格：0.1mg
背景资料：CD80 (B7-1) is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed by dendritic cells, monocytes, and peritoneal macrophages. Expression of CD80 on B cells is upregulated after activation by various means including stimulation by LPS, IL-4, and surface Ig receptor crosslinking with peak expression occurring between 48 and 72 hours post-activation. The interaction of CD80 with its ligands, CD28 and CD152 (CTLA-4), provides a potent costimulatory signal for T cells activated through the CD3/T cell receptor complex. The monoclonal antibody 1G10 blocks binding of CTLA-4 to CD80 but it does not block stimulation of T cells by natural antigen-presenting cells.
保存建议：CD80 抗体 [1G10] (PE-Cy5)-CD80 Antibody [1G10] (PE-Cy5)Store vial at 2-8℃
应用类型：Flow
点击：CD80 抗体 [1G10] (PE-Cy5)-CD80 Antibody [1G10] (PE-Cy5)查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。
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文献和实验: Type 1 (used for FITC, Cy5, and the initial preparation of the Cy5 and Cy7 tandem dyes); Type 2 (used for Biotin and Cascade Blue); Type 3 (used for conjugation of PE, APC, TR-BSA, and their derivatives); and Type 4 (used for the initial preparation
dyes. The conjugations fall into four basic protocols: Type 1 (used for FITC, Cy5, and the initial preparation of the Cy5 and Cy7 tandem dyes); Type 2 (used for Biotin and Cascade Blue); Type 3 (used for conjugation of PE, APC, TR-BSA
，那么它的isotype 是mouse IgG2a， 所以可以用purified（纯化的） mouse IgG2a来做OX-42的同型对照（Isotype Control）。一般的的生物技术公司和国内的代理都有出售。 同型对照：是指与MoAb相同的、未免疫小鼠的免疫球蛋白亚类，若使用直接免疫荧光染色法，同型对照也应标记荧光色素，如IgG1 FITC、IgG2ａ、PE等。主要考虑了细胞的自发荧光、FC受体介导的抗体结合和非特异性抗体结合等影响因素。此外，同型对照与MoAb所标记的荧光色素、浓度、F：P比值（标记的荧
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