- ￥22
- ProSci
- 美国
- PSI-98-767-0.1mg
- 2025年07月15日
- WB, WB-NR, IHC-P, IHC-Fr, Flow, IP
- 大鼠
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
sCD40
- 保存条件：
Store vial at 2-8℃
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
大鼠
- 应用范围：
WB, WB-NR, IHC-P, IHC-Fr, Flow, IP
- 抗体英文名：
CD40 Antibody [1C10] (PE-Cy5)
- 抗体名：
CD40 Antibody [1C10] (PE-Cy5)
- 规格：
0.1mg
CD40 抗体 [1C10] (PE-Cy5)，CD40 Antibody [1C10] (PE-Cy5)，CD40 抗体 [1C10] (PE-Cy5),CD40 Antibody [1C10] (PE-Cy5)
产品名称：CD40 抗体 [1C10] (PE-Cy5)-CD40 Antibody [1C10] (PE-Cy5)
产品货号：PSI-98-767-0.1mg
产品规格：0.1mg
背景资料：CD40 is a type I cell surface protein belonging to the tumor necrosis factor superfamily of cell surface receptors. In mice it is expressed on B lineage cells, follicular dendritic cells, thymic epithelium, and interdigitating cells in the T-cell zone of secondary lymphoid organs. CD40 first becomes detectable on a subset of small pre-B II cells in bone marrow with the levels of CD40 expression increasing thereafter during B cell maturation. Immature B cells (IgM+IgDloB220lo) express intermediate levels of CD40, whereas mature B cells (IgM+IgDhiB220hi) express high levels. CD40 has a central role in B cell growth and differentiation, and signaling through CD40 in combination with IL-4 reportedly induces immunoglobulin isotype switching and secretion of IgE. The agonistic 1C10 antibody closely resembles gp39/CD40 ligand in its ability to stimulate proliferation of small, resting B lymphocytes in the absence of other cofactors.
保存建议：CD40 抗体 [1C10] (PE-Cy5)-CD40 Antibody [1C10] (PE-Cy5)Store vial at 2-8℃
应用类型：WB, WB-NR, IHC-P, IHC-Fr, Flow, IP
点击：CD40 抗体 [1C10] (PE-Cy5)-CD40 Antibody [1C10] (PE-Cy5)查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。
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文献和实验: Type 1 (used for FITC, Cy5, and the initial preparation of the Cy5 and Cy7 tandem dyes); Type 2 (used for Biotin and Cascade Blue); Type 3 (used for conjugation of PE, APC, TR-BSA, and their derivatives); and Type 4 (used for the initial preparation
dyes. The conjugations fall into four basic protocols: Type 1 (used for FITC, Cy5, and the initial preparation of the Cy5 and Cy7 tandem dyes); Type 2 (used for Biotin and Cascade Blue); Type 3 (used for conjugation of PE, APC, TR-BSA
。近年应用于LN治疗，适用于伴发感染或免疫抑制剂不耐受患者，但应用时间尚短，疗效还有待于循征医学的进一步验证。目前用法：每日300～400mg/kg静脉滴注，连续3～5d. 3血液净化疗法LN的血液净化疗法包括：血浆置换（PE）、双重膜血浆滤过（DEPP）、血浆吸附、淋巴细胞清除和粒细胞清除等。除对伴有急性肾衰竭、高冷球蛋白血症、高粘综合征和血栓性血小板减少性紫癜患者PE和DEPP具有一定效果，血浆吸附对伴有高滴度抗DNA抗体的患者有效外，对于一般的LN治疗效果不确定。淋巴细胞清除和粒细胞
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