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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
YAP (phospho Ser127) antibody was raised against a peptide sequence around phosphorylation site of serine127 (A-H-S (p)-S-P) derived from Human YAP .
- 保存条件:
Store antibody at -20℃ for up to one year
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
WB
- 抗体英文名:
YAP (phospho Ser127) Antibody
- 抗体名:
YAP (phospho Ser127) Antibody
- 规格:
0.1mg
YAP (phospho Ser127) 抗体,YAP (phospho Ser127) Antibody,YAP (phospho Ser127) 抗体,YAP (phospho Ser127) Antibody
产品名称:YAP (phospho Ser127) 抗体-YAP (phospho Ser127) Antibody
产品货号:PSI-80-002-0.1mg
产品规格:0.1mg
背景资料:Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Plays a key role to control cell proliferation in response to cell contact.
保存建议:YAP (phospho Ser127) 抗体-YAP (phospho Ser127) AntibodyStore antibody at -20℃ for up to one year
应用类型:WB
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文献和实验【求助】于NF-KB 激活,P65磷酸化位点是ser536还是ser276?
伽利略 ............................... chenlydd 两者都有,蛋白磷酸化水平与其功能密切相关:检测其磷酸化水平可用抗磷酸化位点抗体检测。www.cellsignal.com公司有相应抗体出售。 P65磷酸化位点: regulates apoptosis: S536‑p regulates cell growth: S536‑p regulates cell
Using Phospho‐Motif Antibodies to Determine Kinase Substrates
comprising both the phosphorylated residue and the surrounding residues that determine kinase specificity, with degenerate residues taking up the remaining positions. Currently, several categories of phospho?motif antibody are commercially available
Optimized Protocol to Make Phospho-Specific Antibodies that Work
, not simply its level of expression. In this review, we will discuss both the design of the phosphopeptide immunogen and immunization. The affinity purification of the phospho-specific antibody as well as the methods most suitable for characterizing
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