Akt (phospho Ser473) 抗体-Akt (p

Akt (phospho Ser473) 抗体，Akt (phospho Ser473) Antibody，Akt (phospho Ser473) 抗体,Akt (phospho Ser473) Antibody

产品名称：Akt (phospho Ser473) 抗体-Akt (phospho Ser473) Antibody

产品货号：PSI-79-130-0.1mg

产品规格：0.1mg

背景资料：General protein kinase capable of phosphorylating several known proteins. Phosphorylates TBC1D4. Signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), insulin and insulin-like growth factor I (IGF-I). Plays a role in glucose transport by mediating insulin-induced translocation of the GLUT4 glucose transporter to the cell surface. Mediates the antiapoptotic effects of IGF-I. Mediates insulin-stimulated protein synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462', thereby activating mTORC1 signaling and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1. Promotes glycogen synthesis by mediating the insulin-induced activation of glycogen synthase.

保存建议：Akt (phospho Ser473) 抗体-Akt (phospho Ser473) AntibodyStore antibody at -20℃ for up to one year

应用类型：WB, IHC

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