- ￥22
- ProSci
- 美国
- PSI-33-858-100ug
- 2025年07月14日
- WB, Flow, IHC-P, IF
- 小鼠
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Human p53 beta-galactosidase fusion protein was used as the immunogen for this antibody. Its epitope maps near the N-terminal end (aa 32-79) of p53.
- 保存条件：
Aliquot and Store at 2-8℃
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
小鼠
- 应用范围：
WB, Flow, IHC-P, IF
- 抗体英文名：
p53 Antibody [PAb 1801]
- 抗体名：
p53 Antibody [PAb 1801]
- 规格：
100ug
p53 抗体 [PAb 1801]，p53 Antibody [PAb 1801]，p53 抗体 [PAb 1801],p53 Antibody [PAb 1801]
产品名称：p53 抗体 [PAb 1801]-p53 Antibody [PAb 1801]
产品货号：PSI-33-858-100ug
产品规格：100ug
背景资料：This mAb reacts with an N-terminal epitope (aa 32-79) of both wild type and mutated p53. Mutation and/or allelic loss of p53 is one of the causes of a variety of mesenchymal and epithelial tumors. If it occurs in the germ line, such tumors run in families. In most transformed and tumor cells the concentration of p53 is increased 5-1000 fold over the minute concentrations (1000 molecules cell) in normal cells, principally due to the increased half-life (4 h) compared to that of the wild-type (20 min). It localizes in the nucleus, but is detectable at the plasma membrane during mitosis and when certain mutations modulate cytoplasmic/nuclear distribution. Mutations arise with an average frequency of 70% but incidence varies from zero in carcinoid lung tumors to 97% in primary melanomas. High concentrations of p53 protein are transiently expressed in human epidermis and superficial dermal fibroblasts following mild ultraviolet irradiation. Positive nuclear staining with specific antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia.
保存建议：p53 抗体 [PAb 1801]-p53 Antibody [PAb 1801]Aliquot and Store at 2-8℃
应用类型：WB, Flow, IHC-P, IF
点击：p53 抗体 [PAb 1801]-p53 Antibody [PAb 1801]查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验有anti-phosphothronine 和anti-phosphotyrosine的抗体，PAb和MAb都有，但是没有anti-phosphoserine的抗体。 摘抄： Anti-Phosphothreonine (MAb) - CryptateThe anti-phosphothreonine antibody is a monoclonal antibody (clone 42H4) produced at Cell Signaling
人总P53蛋白(Total P53)ELISA试剂盒 说明书
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 人总P53 蛋白 ( Total P53 )ELISA 试剂盒 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗人 P53 单抗包被于酶标板上，标准品和样品中的 P53与单抗结合，加入生物素化的抗人 P53 ，形成免疫复合物连接在板上，辣根
豚鼠总P53蛋白(Total P53)ELISA试剂盒 说明书
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 豚鼠总P53 蛋白 ( Total P53 )ELISA 试剂盒 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗豚鼠 P53 单抗包被于酶标板上，标准品和样品中的 P53与单抗结合，加入生物素化的抗豚鼠 P53 ，形成免疫复合物连接在板上，辣根
技术资料暂无技术资料 索取技术资料
