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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
An enzymatically glycosylated fragment of human MUC16 recombinant protein was used as the immunogen for the MUC16 antibody.
- 保存条件:
Aliquot and Store at 2-8℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
小鼠
- 应用范围:
IHC-P
- 抗体英文名:
MUC16 Antibody [5E11.]
- 抗体名:
MUC16 Antibody [5E11.]
- 规格:
100ug
MUC16 抗体 [5E11.],MUC16 Antibody [5E11.],MUC16 抗体 [5E11.],MUC16 Antibody [5E11.]
产品名称:MUC16 抗体 [5E11.]-MUC16 Antibody [5E11.]
产品货号:PSI-33-838-100ug
产品规格:100ug
背景资料:The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). Membrane-associated and secretory mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), 6-8, 11-13 and 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions.
保存建议:MUC16 抗体 [5E11.]-MUC16 Antibody [5E11.]Aliquot and Store at 2-8℃
应用类型:IHC-P
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文献和实验Hematopoietic Stem Cell Enrichment From the AGM Region of the Mouse Embryo
in the intraembryonic aorta-gonad-mesonephros region at embryonic day (E) 10.5. After E11, these HSCs are thought to seed the liver and then the bone marrow just before birth. So far, many questions concerning the origin, properties, and functionality of these HSCs
CD35 分子 CD35 常用单克隆抗体或代号: TO5,E11;(CR1) 主要表达细胞: G,M,DC,B,NKsubRBC [M] 分子质量(kDa)和结构: p250(含CCP结构域) 功 能: 结合C3b和C4b,调理吞噬,红细胞免疫粘附,调节B细胞活化 CD35 Aka CR1, C3b and C4b receptor Mediates adherence
甲状腺功能亢进症(简称甲亢)是内分泌领域最常见的疾病之一,核心特征是血液循环中甲状腺激素过量,引发全身代谢亢进与交感神经兴奋,临床常表现为心悸、手抖、多汗、消瘦、易怒等一系列症状。甲亢并非单一病因导致的疾病,而是一组临床综合征。 格雷夫斯病(Graves病)是甲亢最常见病因,约占80%的病例。Graves病是一种自身免疫性疾病,患者产生针对促甲状腺激素受体(TSHR)的自身抗体(TRAb),其中刺激性抗体(TSAb)可模拟促甲状腺激素作用,与TSHR结合持续激活甲状腺细胞,导致T3/T
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