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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Human recombinant full length protein was used as the immunogen for this Thymidine Phosphorylase antibody.
- 保存条件:
Aliquot and Store at 2-8℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
小鼠
- 应用范围:
IHC-P, IP, WB
- 抗体英文名:
Thymidine Phosphorylase Antibody [P-GF.44C]
- 抗体名:
Thymidine Phosphorylase Antibody [P-GF.44C]
- 规格:
100ug
Thymidine Phosphorylase 抗体 [P-GF.44C],Thymidine Phosphorylase Antibody [P-GF.44C],Thymidine Phosphorylase 抗体 [P-GF.44C],Thymidine Phosphorylase Antibody [P-GF.44C]
产品名称:Thymidine Phosphorylase 抗体 [P-GF.44C]-Thymidine Phosphorylase Antibody [P-GF.44C]
产品货号:PSI-33-768-100ug
产品规格:100ug
背景资料:Recognizes a 485 amino acid protein (55 kDa monomer / 110 kDa homodimer), identified as platelet-derived endothelial growth factor (PD-ECGF), also called Thymidine Phosphorylase (TP, Tymp) or Gliostatin. In the presence of inorganic orthophosphate, it catalyzes the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. Its enzymatic activity is crucial for angiogenic activity (metabolite is angiogenic). Higher levels of serum TP/PD-ECGF are observed in cancer patients. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites (e.g. 5 -deoxy-5-fluorouridine to 5-FU). High intra-cellular levels of TP/PD-ECGF are associated with increased chemosensitivity to such antimetabolites.
保存建议:Thymidine Phosphorylase 抗体 [P-GF.44C]-Thymidine Phosphorylase Antibody [P-GF.44C]Aliquot and Store at 2-8℃
应用类型:IHC-P, IP, WB
点击:Thymidine Phosphorylase 抗体 [P-GF.44C]-Thymidine Phosphorylase Antibody [P-GF.44C]查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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文献和实验Real‐Time Quantitative PCR Analysis of Mitochondrial DNA Content
array‐based comparative genomic hybridisation. Arch. Dis. Child 94:55‐58. Nishino, I., Spinazzola, A., and Hirano, M. 1999. Thymidine phosphorylase gene mutations in MNGIE
22 Enhances Thymidine Kinase/Ganciclovir Suicide Gene Therapy for Neuroblastomas Compared to Herpes Simplex Virus VP22 Journal of Virology, Vol. 78, No. 8, Feb. 2004, p.4224-4233 6. Noninvasive Imaging of Cathionic Lipid-Mediated Delivery of Optical
secreting antibody of predefined specificity)的著名论文。他们大胆地把以前不同骨髓瘤细胞之间的融合延伸为将丧失合成次黄嘌呤-鸟嘌呤磷酸核糖转移酶(hypoxanthine guanosine phosphoribosyl transferase,HGPRT)的骨髓瘤细胞与经绵羊红细胞免疫的小鼠脾细胞进行融合。融合由仙台病毒介导,杂交细胞通过在含有次黄嘌呤(hypoxanthine,H)、氨基喋呤(aminopterin,A)和胸腺嘧啶核苷(thymidine,T
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