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- ProSci
- 美国
- PSI-33-747-100ug
- 2025年07月15日
- Flow, WB, IF
- 小鼠
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
A human partial recombinant protein corresponding to the CDH2/NCAD cytoplasmic domain was used as the immunogen for this N-Cadherin antibody.
- 保存条件：
Aliquot and Store at 2-8℃
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
小鼠
- 应用范围：
Flow, WB, IF
- 抗体英文名：
N-Cadherin Antibody [13A9]
- 抗体名：
N-Cadherin Antibody [13A9]
- 规格：
100ug
N-Cadherin 抗体 [13A9]，N-Cadherin Antibody [13A9]，N-Cadherin 抗体 [13A9],N-Cadherin Antibody [13A9]
产品名称：N-Cadherin 抗体 [13A9]-N-Cadherin Antibody [13A9]
产品货号：PSI-33-747-100ug
产品规格：100ug
背景资料：Recognizes a protein of ~140kDa, identified as N-Cadherin (NCAD), also known as CDH2 and CD325. NCAD is a member of the Cadherin superfamily, and consists of five extracellular repeats, a transmembrane domain and a cytoplasmic domain. NCAD/CD325 deficient mice die at day 10 of gestation and embryos display major heart defects and malformed neural tubes and somites. Consistent with this, the protein has been implicated in several aspects of cardiac development including the precardiac mesoderm, establishment of left-right symmetry and cardiac looping morphogenesis. Furthermore, it is normally involved in inducing cell cycle arrest and its expression is frequently deregulated in cancer cells. Studies have linked N-cadherin to cancer metastasis by showing the aggressive tumor cells had preferentially turned on N-cadherin as opposed to E- or P-cadherin.
保存建议：N-Cadherin 抗体 [13A9]-N-Cadherin Antibody [13A9]Aliquot and Store at 2-8℃
应用类型：Flow, WB, IF
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文献和实验上皮及间皮类常用标记抗体EPITHELIAL AND MESOTHELIAL MARKERSCK (MNF 116)- MNF-116 is a pan-cytokeratin antibody.- Source: Dakopatts.- Dilution 1:50.- Antigen retrieval method: HIER (pressure cooking) using EDTA.- Staining pattern: Cytoplasmic, typically
发现E-Cadherin、N-Cadherin、NCAM,CD31及FN和FN受体都与细胞移动有关。（1）在胚胎发育过程中，视神经轴突要沿着视束生长到达中脑顶盖建立突触联系，处于生长状态的轴突在神经表皮细胞表面移动，两者均表达N-Cadherin分子。如将胚胎的视网膜组织种植在单层不表达N-Cadherin的Neuro 2a细胞上，神经轴突不能生长；如果将Neuro 2a细胞转染N-Cadherin分子，则可以看到神经轴突的生长；抗N-Cadherin分子的抗体可以抑制轴突的生长。（2）FN
CD56 分子 CD56 常用单克隆抗体或代号： Leu19,NKH1;(NCAM) 主要表达细胞： NK,Tsub [NK] 分子质量(kDa)和结构： gp180(GPI连接,含FN结构域, 功 能：神经细胞粘附分子(N- CAM) 粘附,诱导杀伤活性 CD56 Aka N-CAM (neural cell adhesion molecule), at #11q23 Regulates homophilic
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