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- ProSci
- 美国
- PSI-33-895-100ug
- 2025年07月10日
- Flow, IF, WB, IHC-P
- 小鼠
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant human protein was used as the immunogen for the Cyclin D1 antibody.
- 保存条件：
Aliquot and Store at 2-8℃
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
小鼠
- 应用范围：
Flow, IF, WB, IHC-P
- 抗体英文名：
Cyclin D1 Antibody [BCLD1-1]
- 抗体名：
Cyclin D1 Antibody [BCLD1-1]
- 规格：
100ug
Cyclin D1 抗体 [BCLD1-1]，Cyclin D1 Antibody [BCLD1-1]，Cyclin D1 抗体 [BCLD1-1],Cyclin D1 Antibody [BCLD1-1]
产品名称：Cyclin D1 抗体 [BCLD1-1]-Cyclin D1 Antibody [BCLD1-1]
产品货号：PSI-33-895-100ug
产品规格：100ug
背景资料：Recognizes a protein of 36kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
保存建议：Cyclin D1 抗体 [BCLD1-1]-Cyclin D1 Antibody [BCLD1-1]Aliquot and Store at 2-8℃
应用类型：Flow, IF, WB, IHC-P
点击：Cyclin D1 抗体 [BCLD1-1]-Cyclin D1 Antibody [BCLD1-1]查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。
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文献和实验Immunodetection of cyclin D1 and D2/D3 using flow cytometry
. It has been tested with antibodies against cyclin D1 (Pharmingen cat. no. 14561A, clone G12-4326), cyclin D2/D3 (cat. no. 14711A, clone G107-22) and cyclin E Procedure Prepare the cell type of interest as a single cell suspension and wash once with cold PBS
Disorders of the cell cycle regulatory machinery play a key role in the pathogenesis of cancer. The gene encoding the cyclin D1 protein, a regulator of the progression from the G1- to S-phase, is often found disrupted in the cancer cell
Immunodetection of cyclin D1 and D2/D3 using 488/630 nm dual laser flow cytometr（图）
. It has been tested with antibodies against cyclin D1 (Pharmingen cat. no. 14561A, clone G12-4326), cyclin D2/D3 (cat. no. 14711A, clone G107-22) and cyclin E, and is based on protocols originally designed by Z. Darzynkiewicz and colleagues. Although FITC-conjugated
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