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- 详细信息
- 技术资料
- 免疫原:
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human cyclin D 1.
- 亚型:
Rabbit Ig
- 形态:
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
多克隆
- 标记物:
见下方详细说明
- 适应物种:
H, M, R
- 保质期:
1-2年
- 抗原来源:
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human cyclin D 1.
- 目录编号:
252030
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Rabbit
- 应用范围:
E, WB
- 浓度:
见详细说明信息
- 靶点:
Cyclin D1
- 抗体英文名:
Cyclin D1 Antibody
- 抗体名:
Cyclin D1 Antibody
- 规格:
0.1 mg
Cyclin D1 Antibody产品详细介绍:
| 产品名称: | Cyclin D1 Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 252030 |
| 规格: | 0.1 mg |
| 产品描述: | G1/S-specific cyclin-D1 (cyclin D1) is essential for the control of the cell cycle at the G1/S (start) transition. Cyclin D1 interacts with the CDK4 and CDK6 protein kinases to form a serine/threonine kinase holoenzyme complex. The cyclin subunit imparts substrate specificity to the complex. Cyclin D1 interacts with FBXO4 and CDKN1B. Cyclin D1 is ubiquitinated, primarily as 'Lys-48'-linked polyubiquitination, by a SCF (SKP1-CUL1-F-box protein) ubiquitin-protein ligase complex containing FBXO4 and CRYAB. Defects in cyclin D1 are a cause of multiple myeloma (MM). MM is a malignant tumor of plasma cells usually arising in the bone marrow and characterized by diffuse involvement of the skeletal system, hyperglobulinemia, Bence-Jones proteinuria and anemia. |
| 克隆类型: | Rabbit Polyclonal Antibody |
| 亚型: | Rabbit Ig |
| 免疫原: | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human cyclin D 1. |
| 适用物种: | H, M, R |
| 应用范围: | E, WB |
| 应用说明: | E: 1:10,000-1:40,000; WB: 1:500-1:1,000 |
| 别名: | Cyclin D1; G1/S-specific cyclin-D1; PRAD1 oncogene; BCL-1 oncogene; BCL1; PRAD1 |
| 形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: |
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Cyclin D1 Antibody_Cyclin D1抗体
¥3000 - 3999










