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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant human protein was used as the immunogen for this CD1a antibody.
- 保存条件:
Aliquot and Store at 2-8℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
小鼠
- 应用范围:
Flow, IHC, IF
- 抗体英文名:
CD1a Antibody [CLDA1a]
- 抗体名:
CD1a Antibody [CLDA1a]
- 规格:
100ug
CD1a 抗体 [CLDA1a],CD1a Antibody [CLDA1a],CD1a 抗体 [CLDA1a],CD1a Antibody [CLDA1a]
产品名称:CD1a 抗体 [CLDA1a]-CD1a Antibody [CLDA1a]
产品货号:PSI-33-869-100ug
产品规格:100ug
背景资料:At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. CD1a antibody labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibody against TTF-1 and CD5, CD1a antibody is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. antibody to CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa).
保存建议:CD1a 抗体 [CLDA1a]-CD1a Antibody [CLDA1a]Aliquot and Store at 2-8℃
应用类型:Flow, IHC, IF
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文献和实验CD1a/CD1b/CD1c/CD1d分子 CD1a 常用单克隆抗体或代号:T6,Leu6 主要表达细胞:Thy,DCsub,LHC,Bsub T细胞 分子质量(kDa)和结构:gp49(IgSF) 功 能:与β2m组成MHCI类样分子,有抗原提呈功能 CD1b 常用单克隆抗体或代号:WM-25,4A7.6,NUT2 主要表达细胞:Thy,DC,LHC,Bsub T细胞 分子
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Th22研究最新进展 文章出处:CD1a-autoreactive T cells are a normal component of the human αβ T cell repertoire. Nat Immunol. 2010. 11(12):1102-1109 主要内容和本人看法: 有关于Th22的相关内容园内已经讨论过多次,很多有识之士都发表了各自的看法。Th22这个名词正式被提出其实是在2009年发表于Nat Immunol的一篇文章(后面文献列表中的第2
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