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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
A recombinant human protein was used as the immunogen for the E-Cadherin antibody.
- 保存条件:
Aliquot and Store at 2-8℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
小鼠
- 应用范围:
Flow, IF, WB, IHC-P
- 抗体英文名:
E-Cadherin Antibody [4A2]
- 抗体名:
E-Cadherin Antibody [4A2]
- 规格:
100ug
E-Cadherin 抗体 [4A2],E-Cadherin Antibody [4A2],E-Cadherin 抗体 [4A2],E-Cadherin Antibody [4A2]
产品名称:E-Cadherin 抗体 [4A2]-E-Cadherin Antibody [4A2]
产品货号:PSI-33-607-100ug
产品规格:100ug
背景资料:Recognizes a protein of 80-120kDa, identified as E-cadherin/CDH1. Cadherins comprise a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of large extracellular domains characterized by a series of five homologous NH2 terminal repeats. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as b-catenin, to regulate cadherin function. E-cadherin plays an important role in epithelial cell adhesion. A decreased expression of E-cadherin is associated with metastatic potential and poor prognosis in breast cancer, prostate and esophageal cancer. In combination with p120 Catenin, it is useful for the differentiation between ductal (E-cadherin +) and lobular (E-cadherin -) breast carcinomas. It may also help in diagnosis of mesothelioma.
保存建议:E-Cadherin 抗体 [4A2]-E-Cadherin Antibody [4A2]Aliquot and Store at 2-8℃
应用类型:Flow, IF, WB, IHC-P
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