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- ProSci
- 美国
- PSI-33-315-100ug
- 2025年07月11日
- Flow, IF, WB, IHC-P
- 小鼠
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- 文献和实验
- 技术资料
- 免疫原：
Recombinant human protein was used as the immunogen for the p27Kip1 antibody.
- 保存条件：
Aliquot and Store at 2-8℃
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
小鼠
- 应用范围：
Flow, IF, WB, IHC-P
- 抗体英文名：
p27Kip1 Antibody [KIP1/769]
- 抗体名：
p27Kip1 Antibody [KIP1/769]
- 规格：
100ug
p27Kip1 抗体 [KIP1/769]，p27Kip1 Antibody [KIP1/769]，p27Kip1 抗体 [KIP1/769],p27Kip1 Antibody [KIP1/769]
产品名称：p27Kip1 抗体 [KIP1/769]-p27Kip1 Antibody [KIP1/769]
产品货号：PSI-33-315-100ug
产品规格：100ug
背景资料：This mAb recognizes a 27kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. This mAb is excellent for staining of formalin-fixed tissues.
保存建议：p27Kip1 抗体 [KIP1/769]-p27Kip1 Antibody [KIP1/769]Aliquot and Store at 2-8℃
应用类型：Flow, IF, WB, IHC-P
点击：p27Kip1 抗体 [KIP1/769]-p27Kip1 Antibody [KIP1/769]查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。
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文献和实验E2F Transcription Factors and pRb Pocket Proteins in Cell Cycle Progression
KIP1 . Therefore, positive and negative signaling events converge on E2F activity resulting in distinct growth-controling and apoptotic activities. Here we describe the immunocytochemical detection of E2F, genomic DNA, BrdU-incorporation, and mitosis
-induced responses, including a down-regulation of the cyclin-dependent kinase (Cdk2) inhibitors p21CIP1 and p27KIP1 , while attachment to P-L-L did not. We conclude that engagement of the FN-receptor integrin α5β1 induces integrin signaling regulating
Functional Analysis of APC-Cdh1
from the end of mitosis to the G1 phase. Loss of Cdh1 induces unscheduled accumulation of mitotic cyclins in G1, resulting in abrogation of G1 arrest caused by treatment with rapamycin, an inducer of p27Kip1 . Furthermore, Cdh1-deficient DT40 cells fail
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