CD20 抗体 [SPM618]-CD20 Antibody

CD20 抗体 [SPM618]，CD20 Antibody [SPM618]，CD20 抗体 [SPM618],CD20 Antibody [SPM618]

产品名称：CD20 抗体 [SPM618]-CD20 Antibody [SPM618]

产品货号：PSI-33-285-100ug

产品规格：100ug

背景资料：This antibody recognizes a protein of 33-37kDa, identified as CD20. The epitope is similar to or identical to that recognized by other CD20 antibodies including Leu-16 and B1. This antibody can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood, Bcell localization in tissues and B lymphocyte purification by immunosorbent methods. CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. It is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. Protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B-cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as a calcium channel involved in B-cell activation and cell cycle progression.

保存建议：CD20 抗体 [SPM618]-CD20 Antibody [SPM618]Aliquot and Store at 2-8℃

应用类型：Flow, IF, IHC

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