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- ProSci
- 美国
- PSI-13-003-50uL
- 2025年07月10日
- WB,IF
- 兔
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human PARP1 (NP_001609.2).
- 保存条件：
Store at -20℃
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
兔
- 应用范围：
WB,IF
- 抗体英文名：
PARP1 Antibody
- 抗体名：
PARP1 Antibody
- 规格：
50uL
PARP1 抗体，PARP1 Antibody，PARP1 抗体,PARP1 Antibody
产品名称：PARP1 抗体-PARP1 Antibody
产品货号：PSI-13-003-50uL
产品规格：50uL
背景资料：This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
保存建议：PARP1 抗体-PARP1 AntibodyStore at -20℃
应用类型：WB,IF
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文献和实验PARP1 Genomics: Chromatin Immunoprecipitation Approach Using Anti-PARP1 Antibody (ChIP and ChIP-seq)
Poly(ADP-ribose) polymerase1 (PARP1) is a global regulator of different cellular mechanisms, ranging from DNA damage repair to control of gene expression. Since PARP1 protein and pADPr have been shown to persist in chromatin through cell
Small-Molecule Collection and High-Throughput Colorimetric Assay to Identify PARP1 Inhibitors
to disrupt the DNA-dependent PARP1 protein activation pathway and were based on a competition with NAD for a binding site on PARP molecule and, therefore, on disruption of PARP-mediated enzymatic reaction. This limitation resulted in a discovery of mainly
在免疫反应方面，基于抗原的刺激在体内形成、并与抗原作特异性结合的蛋白质之总称。其化学实质是免疫球蛋白。抗体，按照抗原抗体反应的类型可分别称为沉淀素、凝集素、溶血素、溶菌素、抗毒素、中和抗体等，但这些并不等于有相应的不同抗体存在，一般多只表明抗体反应的多样性而已。抗体在血清中含量最多（体液抗体=humoral antibody）；含有某特定抗体的血清称为抗血或免疫血清。
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