4E-BP1 抗体 [11G12C11] -4E-BP1 A

4E-BP1 抗体 [11G12C11] ，4E-BP1 Antibody [11G12C11] ，4E-BP1 抗体 [11G12C11] ,4E-BP1 Antibody [11G12C11]

产品名称：4E-BP1 抗体 [11G12C11] -4E-BP1 Antibody [11G12C11]

产品货号：PSI-32-103-0.1mg

产品规格：0.1mg

背景资料：4E-BP1(eukaryotic translation Initiation Factor 4E Binding Protein 1),also called ELF4EBP1/BP-1/PHAS-I ,which is located on chromosome 8p12, with 118-amino acid protein (about 13 kDa). Binding of eIF4EBP1 to eIF4E is reversible and is dependent on the phosphorylation status of eIF4EBP1. Non phosphorylated eIF4EBP1 will bind strongly to eIF4E while(24 kDa), the phosphorylated form will not. Akt, TOR, MAP kinase, S6 kinase, and Cdc2 are known kinases capable of inactivating eIF4EBP1 binding to eIF4E by phosphorylating either threonines 35, 45, 69 or serine 64. Although, not all phosphorylation events equally block the eIF4EBP1-eIF4E interaction.

保存建议：4E-BP1 抗体 [11G12C11] -4E-BP1 Antibody [11G12C11] stored at -20℃, stable for one year

应用类型：IHC

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