CD40 Protein, Rhesus, Recombinant (His Tag)

CD40 Protein, Rhesus, Recombin

ant (His Tag)
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  • $15000
  • Leading Biology
  • 美国
  • PK54254M2
  • 2025年07月07日
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    • 详细信息
    • 技术资料
    • 保存条件

      Stable for 1 year at -4274°C or below from date of shipment.

    • 保质期

      1-2年

    • 供应商

      安诺伦(北京)生物科技有限公司

    • 规格

      1 mg

    蛋白长度:A DNA sequence encoding the rhesus CD40 (NP_001252791.1) (Met 1-Arg193) was expressed with a polyhistidine tag at the C-terminus.

    性质:

    表达系统:HEK293 Cells

    种属:Rhesus

    氨基酸序:Met1-Arg193

    标签类型:C-His

    分子量:The recombinant rhesus CD40 comprises 184 amino acids and has a calculated molecular mass of 20.7 KDa.

    活性:At Leading Biology, the biological activity of a recombinant protein is routinely measured using a bioassay, e.g. chemotaxis or cell proliferation assay, enzyme assay, or a functional ELISA. When a recombinant protein is an enzyme, specific activity is derived from an enzymatic assay. Each enzyme is tested for potency by cleavage of a substrate. We are in the process of updating the biological activity data. If you have any questions regarding this update, please feel free to contact our technical support team.

    内毒素:< 1.0 EU per μg of the protein as determined by the LAL method.

    基因名称:CD40 molecule, TNF receptor superfamily member 5

    通用名:CD40

    蛋白序参考:NP_001252791.1

    总结:CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 protein is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3). In addition, CD40/CD40L interaction is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.

    形式:Lyophilized

    纯度:> 90 % as determined by SDS-PAGE.

    储存条件:In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

    储存溶液:Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.

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