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- 详细信息
- 技术资料
- 保存条件：
Stable for 1 year at -3220°C or below from date of shipment.
- 保质期：
1-2年
- 供应商：
安诺伦（北京）生物科技有限公司
- 规格：
50 ug
蛋白长度：A DNA sequence encoding the mouse LAG3 (NP_032505.1) (Met1-Arg432) was expressed with a polyhistidine tag at the C-terminus.
性质：
表达系统：HEK293 Cells
种属：Mouse
氨基酸序：Met1-Arg432
标签类型：C-His
分子量：The recombinant mouse LAG3 consists of 420 amino acids and predicts a molecular mass of 45.7 kDa. As a result of glycosylation, it migrates as an approximately 55.4 kDa band in SDS-PAGE under reducing conditions.
活性：Measured by its ability to bind FGL1 Protein, Mouse, Recombinant (hFc Tag)(Cat:PM53386M4) in functional ELISA.
内毒素：< 1.0 EU per μg protein as determined by the LAL method.
基因名称：lymphocyte-activation gene 3
通用名：LAG3
蛋白序参考：NP_032505.1
总结：LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signaling, leading to increased antigen-specific T-cell responses in vivo. Diseases associated with LAG3 include Smoldering Myeloma and Kyphoscoliotic Heart Disease.
形式：Lyophilized
纯度：> 90 % as determined by SDS-PAGE.
储存条件：In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
储存溶液：Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
别名：CD223 Protein, Mouse; LAG-3 Protein, Mouse; Ly66 Protein, Mouse
性质：
表达系统：HEK293 Cells
种属：Mouse
氨基酸序：Met1-Arg432
标签类型：C-His
分子量：The recombinant mouse LAG3 consists of 420 amino acids and predicts a molecular mass of 45.7 kDa. As a result of glycosylation, it migrates as an approximately 55.4 kDa band in SDS-PAGE under reducing conditions.
活性：Measured by its ability to bind FGL1 Protein, Mouse, Recombinant (hFc Tag)(Cat:PM53386M4) in functional ELISA.
内毒素：< 1.0 EU per μg protein as determined by the LAL method.
基因名称：lymphocyte-activation gene 3
通用名：LAG3
蛋白序参考：NP_032505.1
总结：LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signaling, leading to increased antigen-specific T-cell responses in vivo. Diseases associated with LAG3 include Smoldering Myeloma and Kyphoscoliotic Heart Disease.
形式：Lyophilized
纯度：> 90 % as determined by SDS-PAGE.
储存条件：In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
储存溶液：Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
别名：CD223 Protein, Mouse; LAG-3 Protein, Mouse; Ly66 Protein, Mouse
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LAG3 Protein, Mouse, Recombinant (ECD, His Tag)
$2305
