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维百奥生物代理Neuro Probe公司产品
美国Neuro Probe公司专业提供用于趋化实验的耗材(Transwell),更好地服务于药筛和基础实验研究领域。着重开发研究细胞活性实验相关的耗材,从第一代用于趋化实验的Boyden Chamer(单孔小室)到48微孔板的趋化小室,再到今天的ChemTx System他们始终与科学实验的步伐保持一致,追求创新,不断地开发新产品以满足多样化的实验需求。
Neuro Probe was founded in the late 1960’s with an initial focus on the development and manufacture of chronic stereotactic equipment. In the early 1970’s, corporate growth and diversification lead to the development and production of chemotactic instruments, beginning with the modified Boyden chamber and then assorted blind well chambers. In 1980, the 48-well microchemotaxis chamber was developed, in collaboration with Dr. Edward Leonard and Dr. Werner Falk working at the National Institutes of Health. This chamber has become a standard in the field and has served as a basis for the development of many new products. Most recently introduced is the ChemoTx® system. Please visit the Products section of our website for more information on specific products.
Neuroprobe的主要产品包括:
ChemoTx®
Chemotaxis Chambers
Single Well Chambers
Filters
Replacement Gaskets
Chemotaxis Accessories
Protein Crystallography
Cell Settling Chambers
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文献和实验体内的一些神经细胞,除具有一般神经元的结构和功能特征外,还有分泌激素的特性,即一种细胞兼有两种细胞特性。它能把神经信号变为由激素中介的化学信号,这类细胞叫神经内分泌细胞。过去认为在高等动物中枢神经系统内,只有少量的神经内分泌细胞,如下丘脑的某些细胞分泌释放或抑制激素。近年发现,神经内分泌细胞在神经系统内并不是少数。脑内有大量神经元含有肽,叫肽能神经元。在中枢神经系统不同部位、脊髓及外周交感神经节中都有肽类,称为脑肽或神经肽。“ P”物质是神经肽中被研究最多的,它在中枢
抑制性递质 inhibitory transmitter,inhi- bitory neuro-transmitter
抑制性递质 inhibitory transmitter, inhi- bitory neuro-transmitter 抑制性突触的化学递质。在中枢神经系统中有γ - 氨基丁酸,甘氨酸和去甲肾上腺素等。但是,有如乙酰胆碱在神经肌肉接头处是兴奋性递质和在心脏的迷走神经末端是抑制性递质那样,化学递质是兴奋性还是抑制性,并不是由物质决定的,而是取决于它所作用的突触下膜的离子通透性和细胞内的离子浓度(主要是氯离子)。
Prehybridization and probe labeling
1 mL TOTAL 200 mL Prehybridize membranes for at least 6 hours to overnight. Probe labeling Heat water to boiling
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