Invitrogen货号A32902现货Human PKMY

Invitrogen货号A32902现货Human PKMYT1，GST Tag Recombinant Protein上海睿安生物13611631389

产品详细信息:For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. This PKMYT1 recombinant human protein (full length) was expressed in insect cells. PKMYT1 recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service. • Validated for use with the LanthaScreen™ Eu Kinase Binding assay • Available in multiple pack sizes for convenient use • Also available in our SelectScreen Kinase Profiling Service Protein Form: Recombinant, Full Length
靶标信息:PKMYT1 serine/threonine kinase is a member of a family of neural specific, zinc finger-containing DNA-binding proteins which binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system. MYT1 of the oligodendrocyte lineage, along with a closely related CCHC zinc finger, is expressed in developing neurons in the mammalian central nervous system. The recombinant PKMYT1 fragments containing either the upstream 2 zinc fingers or the downstream 4 zinc fingers bound the same cis regulatory element in the PLP1 promoter in vitro and DNA binding required Zn2+, but not other divalent cations.

产品详细信息:
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.
This PKMYT1 recombinant human protein (full length) was expressed in insect cells.
PKMYT1 recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service.
•Validated for use with the LanthaScreen™ Eu Kinase Binding assay
•Available in multiple pack sizes for convenient use
•Also available in our SelectScreen Kinase Profiling Service

Protein Form: Recombinant,Full Length

靶标信息:

PKMYT1 serine/threonine kinase is a member of a family of neural specific, zinc finger-containing DNA-binding proteins which binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system. MYT1 of the oligodendrocyte lineage, along with a closely related CCHC zinc finger, is expressed in developing neurons in the mammalian central nervous system. The recombinant PKMYT1 fragments containing either the upstream 2 zinc fingers or the downstream 4 zinc fingers bound the same cis regulatory element in the PLP1 promoter in vitro and DNA binding required Zn2+, but not other divalent cations.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

产品详细信息:
为了最大限度地恢复，请在使用前旋转。除非下文另有说明，否则不建议等分5µg、10µg和20µg大小的激酶，因为材料可以在原始包装中使用，直到用完。对于较大的尺寸，可以通过制备等分试样来减少冷冻/解冻的次数，不建议使用低于20µL的等分试样。请不要储存稀释过的激酶。如果在-80摄氏度下正确储存，本产品自购买之日起可保证使用6个月。
该PKMYT1重组人蛋白（全长）在昆虫细胞中表达。
PKMYT1重组人蛋白也可在我们的SelectScreen中获得™激酶分析服务。
•经验证可与LanthaScreen一起使用™EEu激酶结合测定
•有多种包装尺寸可供选择，使用方便
•也可在我们的SelectScreen激酶分析服务中获得
蛋白质形式：重组，全长

靶标信息:
PKMYT1丝氨酸/苏氨酸激酶是一个含有锌指的神经特异性DNA结合蛋白家族的成员，其与中枢神经系统蛋白脂蛋白的启动子区结合，并在发育中的神经系统中发挥作用。少突胶质细胞谱系的MYT1，以及密切相关的CCHC锌指，在哺乳动物中枢神经系统的发育神经元中表达。含有上游2个锌指或下游4个锌指的重组PKMYT1片段在体外结合PLP1启动子中的相同顺式调节元件，并且DNA结合需要Zn2+，但不需要其他二价阳离子。