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- 文献和实验
- 技术资料
- 供应商:
齐源
- 库存:
999
- 靶点:
CD204
- 级别:
CD204 Antibody
- 目录编号:
CD204 Antibody
- 克隆性:
单克隆
- 抗原来源:
大鼠
- 保质期:
CD204 Antibody
- 抗体英文名:
TotalSeq™-A0448 anti-mouse CD204 Antibody
- 抗体名:
CD204 Antibody
- 标记物:
CD204 Antibody
- 宿主:
大鼠
- 适应物种:
小鼠
- 免疫原:
CD204 Antibody
- 亚型:
CD204 Antibody
- 形态:
CD204 Antibody
- 应用范围:
PG
- 保存条件:
2-8℃
- 浓度:
0.5 mg/ml
- 规格:
10 ug
Description :CD204, also known as scavenger receptor A (SR-A) and the macrophage scavenger receptor(MSR), is 220 kDa, trimeric type II transmembrane protein, with one scavenger receptorcysteine-rich domain (SRCR). It is a phagocytic pattern-recognition receptor (PRR) expressedon macrophages and dendritic cells. CD204 is a receptor mediating recognition andinternalization of low-density lipoprotein (LDL) by macrophages and plays a critical role inatherogenesis. CD204 also recognizes apoptotic cells, modified lipid proteins, and exogenouspathogen-associated molecular patterns (PAMPs), which results in the induction of innateimmune and inflammatory responses. CD204 can act as a co-receptor for Toll-like receptors,such as TLR3, TLR4, or TLR9, to facilitate the expression of proinflammatory cytokines.CD204 has been implicated in several pathological processes such as Alzheimer’s disease,sepsis, ischemic injury, and coronary artery disease.
Verified Reactivity :Mouse
Antibody Type :Monoclonal
Host Species :Rat
Immunogen :Recombinant mouse CD204 extracellular domain
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 1 mM EDTA.
Preparation :The antibody was purified by chromatography and conjugated with TotalSeq™-A oligomer underoptimal conditions.
Concentration :0.5 mg/ml
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
Application :PG - Quality tested
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis and the oligomer sequence is confirmed by sequencing. TotalSeq™-A antibodies arecompatible with 10x Genomics Single Cell Gene Expression Solutions.
To maximize performance, it is strongly recommended that the reagent be titrated for eachapplication, and that you centrifuge the antibody dilution before adding to the cells at 14,000xg at 2- 8°C for 10 minutes. Carefully pipette out the liquid avoiding the bottom of the tube and add to thecell suspension. For Proteogenomics analysis, the suggested starting amount of this reagent fortitration is ≤ 1.0 µg per million cells in 100 µL volume. Refer to the corresponding TotalSeq™protocol for specific staining instructions.
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文献和实验1. Al-Rifai R, et al. 2022. Nat Commun. 13:6592. PubMed
大学的Andrew Chalmers博士于2014年主导创立的,其号称是世界最大的抗体搜索引擎,该网站上包含了来自204个抗体供应商的近五百万个抗体,汇总了两百多万条抗体引用数据,并且该网站仍在不断更新最新的数据。输入关键词(如:CD3)后点击搜索即可出现所有符合条件的抗体,而该网站的特色是,搜索结果根据抗体被文献引用的次数排序,一般来说,引用越多的产品,质量往往越有保证。 03 Labome 网址:https://www.labome.com/ Labome(www.labome.com
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