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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
986
- 靶点：
β2-microglobulin
- 级别：
β2-microglobulin Antibody
- 目录编号：
β2-microglobulin Antibody
- 克隆性：
单克隆
- 抗原来源：
小鼠
- 保质期：
β2-microglobulin Antibody
- 抗体英文名：
anti-human β2-microglobulin Antibody-APC
- 抗体名：
β2-microglobulin Antibody
- 标记物：
APC
- 宿主：
小鼠
- 适应物种：
人
- 免疫原：
β2-microglobulin Antibody
- 亚型：
β2-microglobulin Antibody
- 形态：
β2-microglobulin Antibody
- 应用范围：
FC
- 保存条件：
2-8℃
- 浓度：
β2-microglobulin Antibody
- 规格：
25 tests/100 tests
| 规格： | 25 tests | 产品价格： | ￥2100.0 |
|---|---|---|---|
| 规格： | 100 tests | 产品价格： | ￥5400.0 |
anti-human β2-microglobulin Antibody-APC详细如下：
Description ：β2-microglobulin (β2M) is a 12 kD nonpolymorphic Ig like protein. It is a non-membraneanchored glycoprotein and is noncovalently associated with 39-44 kD polymorphic heavychains of MHC class I molecules to form HLA class I antigen complex. In association with HLAclass I, β2M is expressed on all leukocytes, platelets, endothelial cells, and epithelial cells. β2Mplays an essential role both in governing MHC class I molecules stability and in promotingantigen binding and presenting the antigen to CD3/TCR complex of CD8 T cells.
Verified Reactivity ：Human
Reported Reactivity ：African Green, Baboon, Cynomolgus, Rhesus, Pig
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：Purified human β2-microglobulin
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation ：The antibody was purified by affinity chromatography and conjugated with APC under optimalconditions.
Concentration ：Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：FC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in100 µl staining volume or 5 µl per 100 µl of whole blood.
Excitation Laser ：Red Laser (633 nm)
Description ：β2-microglobulin (β2M) is a 12 kD nonpolymorphic Ig like protein. It is a non-membraneanchored glycoprotein and is noncovalently associated with 39-44 kD polymorphic heavychains of MHC class I molecules to form HLA class I antigen complex. In association with HLAclass I, β2M is expressed on all leukocytes, platelets, endothelial cells, and epithelial cells. β2Mplays an essential role both in governing MHC class I molecules stability and in promotingantigen binding and presenting the antigen to CD3/TCR complex of CD8 T cells.
Verified Reactivity ：Human
Reported Reactivity ：African Green, Baboon, Cynomolgus, Rhesus, Pig
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：Purified human β2-microglobulin
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation ：The antibody was purified by affinity chromatography and conjugated with APC under optimalconditions.
Concentration ：Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：FC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in100 µl staining volume or 5 µl per 100 µl of whole blood.
Excitation Laser ：Red Laser (633 nm)
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文献和实验该产品被引用文献
Application References(PubMed link indicatesBioLegend citation)：
1. Meissner TB, et al. 2010. Proc Natl Acad Sci USA. PubMed
2. Rizvi SM, et al. 2011. J. Immunol. 186:2309. PubMed
3. Meissner TB, et al. 2012. J Immunol. 188:4951. PubMed.
Product Citations：
1. Chung H et al. 2018. Cell. 172(4):811-824 . PubMed
2. Mitchell K, et al. 2018. J Exp Med. 215:1709. PubMed
3. Zhuang X, et al. 2020. Front Immunol. 2.415972222. PubMed
4. Gondim M, et al. 2015. J Virol. 89: 12518 - 12524. PubMed
5. Li YR, et al. 2021. Cell Rep Med. 2:100449. PubMed
6. Kishton RJ, et al. 2022. Cell Rep. 40:111153. PubMed
7. DeWeirdt PC, et al. 2020. Nat Biotechnol. . PubMed
8. Hamilton JR, et al. 2021. Cell Reports. 35(9):109207. PubMed
9. Haideri T, et al. 2022. Cell Rep Methods. 2:100290. PubMed
10. Xu X, et al. 2018. Sci Rep. 8:11649. PubMed
11. Song S, et al. 2021. Front Immunol. 12:705140. PubMed
1. Meissner TB, et al. 2010. Proc Natl Acad Sci USA. PubMed
2. Rizvi SM, et al. 2011. J. Immunol. 186:2309. PubMed
3. Meissner TB, et al. 2012. J Immunol. 188:4951. PubMed.
Product Citations：
1. Chung H et al. 2018. Cell. 172(4):811-824 . PubMed
2. Mitchell K, et al. 2018. J Exp Med. 215:1709. PubMed
3. Zhuang X, et al. 2020. Front Immunol. 2.415972222. PubMed
4. Gondim M, et al. 2015. J Virol. 89: 12518 - 12524. PubMed
5. Li YR, et al. 2021. Cell Rep Med. 2:100449. PubMed
6. Kishton RJ, et al. 2022. Cell Rep. 40:111153. PubMed
7. DeWeirdt PC, et al. 2020. Nat Biotechnol. . PubMed
8. Hamilton JR, et al. 2021. Cell Reports. 35(9):109207. PubMed
9. Haideri T, et al. 2022. Cell Rep Methods. 2:100290. PubMed
10. Xu X, et al. 2018. Sci Rep. 8:11649. PubMed
11. Song S, et al. 2021. Front Immunol. 12:705140. PubMed
文献支持
抗人 β2-微球蛋白荧光标记APC 抗体
￥2100 - 5400
