TotalSeq™-C0869 抗人 CD365 (Tim-

TotalSeq™-C0869 anti-human CD365 (Tim-1) Antibody详细如下：

Description ：CD365 (Tim-1) is a transmembrane glycoprotein expressed on activated CD4 lymphocytesespecially on Th2 cells. It has been implicated to play a critical role in the development ofatopic disease and other Th2-biased immune responses. Tim-1 is a hepatitis A virus receptorin humans. Tim-4 is the endogenous ligand of Tim-1. The interaction of Tim-1 and Tim-4 isinvolved in the costimulation of T cell proliferation. Tim-1 has been reported to be anendogenous ligand for LMIR5 (Leukocyte mono-immunoglobulin (Ig)-like receptor 5), and theTim-1-LMIR5 interaction plays a physiological role in immune regulation by myeloid cells.

Verified Reactivity ：Human

Antibody Type ：Monoclonal

Host Species ：Mouse

Immunogen ：Human TIM-1-IgV Fc

Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 1 mM EDTA

Preparation ：The antibody was purified by chromatography and conjugated with TotalSeq™-C oligomer underoptimal conditions.

Concentration ：0.5 mg/mL

Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.

Application ：PG - Quality tested

Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis and the oligomer sequence is confirmed by sequencing. TotalSeq™-C antibodies arecompatible with 10x Genomics Chromium Single Cell Immune Profiling Solution.

To maximize performance, it is strongly recommended that the reagent be titrated for eachapplication, and that you centrifuge the antibody dilution before adding to the cells at 14,000xg at 2- 8°C for 10 minutes. Carefully pipette out the liquid avoiding the bottom of the tube and add to thecell suspension. For Proteogenomics analysis, the suggested starting amount of this reagent fortitration is ≤ 1.0 µg per million cells in 100 µL volume. Refer to the corresponding TotalSeq™protocol for specific staining instructions.