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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
999
- 靶点：
TSLPR (TSLP-R)
- 级别：
TSLPR (TSLP-R) Antibody
- 目录编号：
TSLPR (TSLP-R) Antibody
- 克隆性：
单克隆
- 抗原来源：
小鼠
- 保质期：
TSLPR (TSLP-R) Antibody
- 抗体英文名：
Cyanine5.5 anti-human TSLPR (TSLP-R) Antibody/PerCP
- 抗体名：
TSLPR (TSLP-R) Antibody
- 标记物：
PerCP
- 宿主：
小鼠
- 适应物种：
人
- 免疫原：
TSLPR (TSLP-R) Antibody
- 亚型：
TSLPR (TSLP-R) Antibody
- 形态：
TSLPR (TSLP-R) Antibody
- 应用范围：
FC
- 保存条件：
2-8℃
- 浓度：
TSLPR (TSLP-R) Antibody
- 规格：
100 tests
Description ：TSLP-R, also known as the thymic stromal lymphopoietin protein receptor, cytokine receptorlike 2, CRL2, and IL-XR, is a type I membrane receptor that forms a functional heterodimericcomplex with IL-7R to bind with TSLP. The TSLP-R contains a WSXWS motif required forproper protein folding and a box1 motif important for association with the JAKs. TSLP-R has apredicted molecular weight approximately 40 kD, and has two isoforms reported that areproduced by alternative splicing. The TSLP-R is expressed preferentially in myeloid cells,dendritic cells, and activated monocytes. It is weakly expressed in T cells. Expression has alsobeen reported in heart, skeletal, muscle, and kidney tissues. TSLP binding to the heterodimericfunctional receptor (TSLP-R and IL-7R) activates JAK2, STAT3, and STAT5 to stimulate cellproliferation. Ligand receptor interactions have been implicated in the development of thehematopoietic system, dendritic cell maturation, and the maintenance and polarization ofhuman Th2 memory T cells in allergy diseases.
Verified Reactivity ：Human
Reported Reactivity ：Baboon
Antibody Type ：Monoclonal
Host Species ：Mouse
Immunogen ：Human TSLP-R:Fc protein
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation ：The antibody was purified by affinity chromatography and conjugated with PerCP/Cyanine5.5under optimal conditions.
Concentration ：Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentrationand Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：FC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in100 µl staining volume or 5 µl per 100 µl of whole blood.
* PerCP/Cyanine5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.
Excitation Laser ：Blue Laser (488 nm)
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文献和实验R&D Systems:如何提高MSC的扩增且不损失其分化潜能
。人MSCs （hMSCs ） 购于Cambr e x （ Lonz a ,Walkersville），先根据供应商的说明书培养，然后用StemXVivo人/小鼠骨髓间充质干细胞扩增培养基（ 目录# C C M 0 0 4 ； R & DSystems，Minneapolis）培养。为了测试不同批次FBS的扩增潜能，每种F B S 以终浓度为1 0 % 或2 0 % 加入含有谷氨酰胺， 丙酮酸钠（ I r v i n e S c i e n t i c ， S a n t a A n a ） 的α
Fluorochrome Absorption and Emission Spectra
. Due to its photobleaching characteristics, PerCP conjugates are not recommended for use on stream-in-air flow cytometers. PerCP-Cy5.5 is a tandem conjugate system than combines PerCP with a cyanine dye (Cy5.5™) and has an absorption maximum
Fluorochrome Absorption and Emission
. Due to its photobleaching characteristics, PerCP conjugates are not recommended for use on stream-in-air flow cytometers. PerCP-Cy5.5 is a tandem conjugate system than combines PerCP with a cyanine dye (Cy5.5™) and has an absorption maximum
