抗人 TSLPR (TSLP-R) 荧光标记APC 抗体

anti-human TSLPR (TSLP-R) Antibody-APC详细如下：

Description ：TSLP-R, also known as the thymic stromal lymphopoietin protein receptor, cytokine receptorlike 2, CRL2, and IL-XR, is a type I membrane receptor that forms a functional heterodimericcomplex with IL-7R to bind with TSLP. The TSLP-R contains a WSXWS motif required forproper protein folding and a box1 motif important for association with the JAKs. TSLP-R has apredicted molecular weight approximately 40 kD, and has two isoforms reported that areproduced by alternative splicing. The TSLP-R is expressed preferentially in myeloid cells,dendritic cells, and activated monocytes. It is weakly expressed in T cells. Expression has alsobeen reported in heart, skeletal, muscle, and kidney tissues. TSLP binding to the heterodimericfunctional receptor (TSLP-R and IL-7R) activates JAK2, STAT3, and STAT5 to stimulate cellproliferation. Ligand receptor interactions have been implicated in the development of thehematopoietic system, dendritic cell maturation, and the maintenance and polarization ofhuman Th2 memory T cells in allergy diseases.

Verified Reactivity ：Human

Reported Reactivity ：Baboon

Antibody Type ：Monoclonal

Host Species ：Mouse

Immunogen ：Human TSLP-R:Fc protein

Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)

Preparation ：The antibody was purified by affinity chromatography, and conjugated with APC under optimalconditions.

Concentration ：Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)

Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.

Application ：FC - Quality tested

Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in100 µl staining volume or 5 µl per 100 µl of whole blood.

Excitation Laser ：Red Laser (633 nm)