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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
齐源
- 库存:
999
- 靶点:
CD270
- 级别:
CD270 (HVEM, TR2) Antibody
- 目录编号:
CD270 (HVEM, TR2) Antibody
- 克隆性:
单克隆
- 抗原来源:
小鼠
- 保质期:
CD270 (HVEM, TR2) Antibody
- 抗体英文名:
Dazzle™ 594 anti-human CD270 (HVEM, TR2) Antibody-PE
- 抗体名:
CD270 (HVEM, TR2) Antibody
- 标记物:
PE
- 宿主:
小鼠
- 适应物种:
人
- 免疫原:
CD270 (HVEM, TR2) Antibody
- 亚型:
CD270 (HVEM, TR2) Antibody
- 形态:
CD270 (HVEM, TR2) Antibody
- 应用范围:
FC
- 保存条件:
2-8℃
- 浓度:
CD270 (HVEM, TR2) Antibody
- 规格:
25 tests/100 tests
| 规格: | 25 tests | 产品价格: | ¥3000.0 |
|---|---|---|---|
| 规格: | 100 tests | 产品价格: | ¥6500.0 |
Dazzle™ 594 anti-human CD270 (HVEM, TR2) Antibody-PE详细如下:
Description :The 122 antibody recognizes human HVEM also known as herpesvirus entry mediator A, tumornecrosis factor receptor superfamily, member 14, TNFRSF14, and tumor necrosis factorreceptor like 2. HVEM, a member of the TNFR superfamily, is a type I transmembrane proteincontaining 2 TNF receptor domains with a predicted molecular weight of approximately 30 kD.HVEM is widely expressed in blood vessels, brain, heart, kidney, liver, lung, prostate, spleen,thymus and other organs. Resting T cells and naïve and memory B cells express high levels ofHVEM as well. In humans, HVEM is not expressed in germinal center B cells. Immature dendriticcells express high levels of HVEM that is downregulated upon maturation. HVEM plays animportant role in herpes simplex virus pathogenesis by enhancing entry into cells. Signalingthrough HVEM activates JNK1, NF-κB and AP-1 to control gene expression in response toinfection or cellular stress and activate the immune response. HVEM binds to LIGHT and hasalso been shown to associate with several other proteins including TRAF1, TRAF2, TRAF3,TRAF5, B and T lymphocyte associated protein (BTLA), and estrogen receptor alpha.
Verified Reactivity :Human
Reported Reactivity :African Green, Baboon, Cynomolgus, Rhesus
Antibody Type Monoclonal
Host Species :Mouse
Immunogen :Recombinant human HVEM protein
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Concentration :Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Application :FC - Quality tested
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in100 µl staining volume or 5 µl per 100 µl of whole blood.
* PE/Dazzle™ 594 has a maximum excitation of 566 nm and a maximum emission of 610 nm.
Excitation Laser :Blue Laser (488 nm)、Green Laser (532 nm)、Yellow-Green Laser (561 nm)
Description :The 122 antibody recognizes human HVEM also known as herpesvirus entry mediator A, tumornecrosis factor receptor superfamily, member 14, TNFRSF14, and tumor necrosis factorreceptor like 2. HVEM, a member of the TNFR superfamily, is a type I transmembrane proteincontaining 2 TNF receptor domains with a predicted molecular weight of approximately 30 kD.HVEM is widely expressed in blood vessels, brain, heart, kidney, liver, lung, prostate, spleen,thymus and other organs. Resting T cells and naïve and memory B cells express high levels ofHVEM as well. In humans, HVEM is not expressed in germinal center B cells. Immature dendriticcells express high levels of HVEM that is downregulated upon maturation. HVEM plays animportant role in herpes simplex virus pathogenesis by enhancing entry into cells. Signalingthrough HVEM activates JNK1, NF-κB and AP-1 to control gene expression in response toinfection or cellular stress and activate the immune response. HVEM binds to LIGHT and hasalso been shown to associate with several other proteins including TRAF1, TRAF2, TRAF3,TRAF5, B and T lymphocyte associated protein (BTLA), and estrogen receptor alpha.
Verified Reactivity :Human
Reported Reactivity :African Green, Baboon, Cynomolgus, Rhesus
Antibody Type Monoclonal
Host Species :Mouse
Immunogen :Recombinant human HVEM protein
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Concentration :Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in ourCertificate of Analysis online tool.)
Application :FC - Quality tested
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in100 µl staining volume or 5 µl per 100 µl of whole blood.
* PE/Dazzle™ 594 has a maximum excitation of 566 nm and a maximum emission of 610 nm.
Excitation Laser :Blue Laser (488 nm)、Green Laser (532 nm)、Yellow-Green Laser (561 nm)
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文献和实验该产品被引用文献
Application References(PubMed link indicatesBioLegend citation):
1. Cheung TC, et al. 2010. J. Immunol. 185:1949. PubMed
2. Hobo W, et al. 2012. J Immunol. 189:39. PubMed.
1. Cheung TC, et al. 2010. J. Immunol. 185:1949. PubMed
2. Hobo W, et al. 2012. J Immunol. 189:39. PubMed.
文献支持
Dazzle™ 594 抗人 CD270 (HVEM, TR2) 荧光标记PE 抗体
¥3000 - 6500










