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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
齐源
- 库存:
999
- 靶点:
CD226
- 级别:
CD226 (DNAM-1) Antibody
- 目录编号:
CD226 (DNAM-1) Antibody
- 克隆性:
单克隆
- 抗原来源:
小鼠
- 保质期:
CD226 (DNAM-1) Antibody
- 抗体英文名:
TotalSeq™-B0368 anti-human CD226 (DNAM-1) Antibody
- 抗体名:
CD226 (DNAM-1) Antibody
- 标记物:
CD226 (DNAM-1) Antibody
- 宿主:
小鼠
- 适应物种:
人
- 免疫原:
CD226 (DNAM-1) Antibody
- 亚型:
CD226 (DNAM-1) Antibody
- 形态:
CD226 (DNAM-1) Antibody
- 应用范围:
PG
- 保存条件:
2-8℃
- 浓度:
0.5 mg/mL
- 规格:
10 µg
Description :DNAM-1 (CD226) is a ~65 kD glycoprotein expressed on cell surface of T cells, NK cells,monocytes/macrophages, platelets and megakaryocytes and a subset of B cells and a memberof the immunoglobulin (Ig)-superfamily containing 2 Ig-like domains of the V-set. The ligandsfor CD226 are the poliovirus receptor (CD155) and its family member nectin-2 (CD112), whichare broadly expressed on epithelial, endothelial and neuronal cells. CD226 is physicallyassociated with LFA-1 in NK cells and activated T cells, and involved in LFA-1-mediatedsignaling.
Verified Reactivity :Human
Reported Reactivity :African Green, Baboon, Cynomolgus, Rhesus
Antibody Type :Monoclonal
Host Species :Mouse
Formulation :Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 1 mM EDTA
Preparation :The antibody was purified by chromatography and conjugated with TotalSeq™-B oligomer underoptimal conditions.
Concentration :0.5 mg/mL
Storage & Handling :The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
Application :PG - Quality tested
Recommended Usage :Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis and the oligomer sequence is confirmed by sequencing. TotalSeq™-B antibodies arecompatible with 10x Genomics Single Cell Gene Expression Solutions.
To maximize performance, it is strongly recommended that the reagent be titrated for eachapplication, and that you centrifuge the antibody dilution before adding to the cells at 14,000xg at 2- 8°C for 10 minutes. Carefully pipette out the liquid avoiding the bottom of the tube and add to thecell suspension. For Proteogenomics analysis, the suggested starting amount of this reagent fortitration is ≤ 1.0 µg per million cells in 100 µL volume. Refer to the corresponding TotalSeq™protocol for specific staining instructions.
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文献和实验1. Fuchs A, et al. 2004. J. Immunol. 172:3994.
中科院高福院士课题组 2019 年发表了哪些重要的研究成果?
of the side-by-side two-IgV molecule CD226 /DNAM- 1 to its ligand CD155 /Necl- 5(并排的两个 IgV 分子 CD226 / DNAM- 1 与配体 CD155 / Necl- 5 的结合模式)CD226 /DNAM- 1 是一种在 NK 细胞中表达的刺激分子,它通过与 NK 细胞的配体 CD155 结合来调节 NK 细胞的功能。研究人员通过测定载脂蛋白 CD226 和 CD226 -CD155 复合物的结构,探讨激活受体 CD226 和 CD155 相互作用的分子
R&D Systems 适用于神经细胞培养的无血清培养基添加剂
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