- ￥3900
- 齐源
- 121206
- 国产/进口
- 2025年07月14日
- FC
- 大鼠
- 小鼠
6 年钻石会员
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 供应商：
齐源
- 库存：
999
- 靶点：
CD43 Activation
- 级别：
CD43 Activation-Associated Glycoform Antibody
- 目录编号：
CD43 Activation-Associated Glycoform Antibody
- 克隆性：
单克隆
- 抗原来源：
大鼠
- 保质期：
CD43 Activation-Associated Glycoform Antibody
- 抗体英文名：
anti-mouse CD43 Activation-Associated Glycoform Antibody-FITC
- 抗体名：
CD43 Activation-Associated Glycoform Antibody
- 标记物：
FITC
- 宿主：
大鼠
- 适应物种：
小鼠
- 免疫原：
CD43 Activation-Associated Glycoform Antibody
- 亚型：
CD43 Activation-Associated Glycoform Antibody
- 形态：
CD43 Activation-Associated Glycoform Antibody
- 应用范围：
FC
- 保存条件：
2-8℃
- 浓度：
0.5 mg/ml
- 规格：
200 µg
anti-mouse CD43 Activation-Associated Glycoform Antibody-FITC详细如下：
Description ：CD43, also known as Ly-48, Leukosialin, Sialophorin, Leukocyte Sialoglycoprotein, and gp115,is a large single chain of type I transmembrane glycoprotein with abundant O-glycosylation andsialylation sites. Due to variable glycosylation and sialylation, two isoforms of CD43 have beenidentified. The 115 kD glycoform of CD43 is expressed on most hematopietic cells including Tlymphocytes, NK cells, monocytes, granulocytes, platelets, and CD5 B cells. It is not presenton resting B cells and erythrocytes. While the 130 kD glycoform is thought to be activationassociated form primarily expressed on myeloid cells, pre-B cells, and activated T cells. It hasbeen reported that CD43 binds to CD54 and Siglec-1. CD43 plays dual roles in cell adhesionand anti-adhesion, as well as costimulation of T cell activation and survival, and induction ofapoptosis of T cells and hematopoietic progenitors. The 1B11 antibody reacts with theactivation-associated glycoform of CD43. The epitope recognized by 1B11 is also shared withdesialylated CD45RB. This antibody is useful for differentiation of effector CD8 T cells andmemory T cells.
Verified Reactivity ：Mouse
Antibody Type ：Monoclonal
Host Species ：Rat
Immunogen ：Mouse WEHI 274.3 myeloid tumor cells
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation ：The antibody was purified by affinity chromatography, and conjugated with FITC under optimalconditions.
Concentration ：0.5 mg/ml
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：FC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10 cells in100 µl. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser ：Blue Laser (488 nm)
Description ：CD43, also known as Ly-48, Leukosialin, Sialophorin, Leukocyte Sialoglycoprotein, and gp115,is a large single chain of type I transmembrane glycoprotein with abundant O-glycosylation andsialylation sites. Due to variable glycosylation and sialylation, two isoforms of CD43 have beenidentified. The 115 kD glycoform of CD43 is expressed on most hematopietic cells including Tlymphocytes, NK cells, monocytes, granulocytes, platelets, and CD5 B cells. It is not presenton resting B cells and erythrocytes. While the 130 kD glycoform is thought to be activationassociated form primarily expressed on myeloid cells, pre-B cells, and activated T cells. It hasbeen reported that CD43 binds to CD54 and Siglec-1. CD43 plays dual roles in cell adhesionand anti-adhesion, as well as costimulation of T cell activation and survival, and induction ofapoptosis of T cells and hematopoietic progenitors. The 1B11 antibody reacts with theactivation-associated glycoform of CD43. The epitope recognized by 1B11 is also shared withdesialylated CD45RB. This antibody is useful for differentiation of effector CD8 T cells andmemory T cells.
Verified Reactivity ：Mouse
Antibody Type ：Monoclonal
Host Species ：Rat
Immunogen ：Mouse WEHI 274.3 myeloid tumor cells
Formulation ：Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation ：The antibody was purified by affinity chromatography, and conjugated with FITC under optimalconditions.
Concentration ：0.5 mg/ml
Storage & Handling ：The antibody solution should be stored undiluted between 2°C and 8°C, and protected fromprolonged exposure to light. Do not freeze.
Application ：FC - Quality tested
Recommended Usage ：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometricanalysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10 cells in100 µl. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser ：Blue Laser (488 nm)
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验该产品被引用文献
Application References(PubMed link indicatesBioLegend citation)：
1. Jones AT, et al. 1994. J. Immunol. 153:3426. (IP, WB)
2. Carlow DA, et al. 1999. J. Immunol. 163:1441. (IP, WB)
3. Onami TM, et al. 2002. J. Immunol. 168:6022.
4. van der Most RG, et al. 2003. Intl. Immunol. 15:119.
5. Chu VT, et al. 2007. J. Immunol. 179:5947.
6. Lang A, et al. 2008. J. Immunol. 180:4848. PubMed
7. Gibbert K, et al. 2010. J. Immunol. 185:6179. PubMed
Product Citations：
1. Barrett N, et al. 2016. Cell Rep. 16: 1039-1054. PubMed
2. Rubinstein M, et al. 2008. Blood. 112:3704. PubMed
3. Bánki Z, et al. 2010. PLoS One. 5:e1000891. PubMed
4. Kidder D, et al. 2013. J Immunol. 190:2593. PubMed
1. Jones AT, et al. 1994. J. Immunol. 153:3426. (IP, WB)
2. Carlow DA, et al. 1999. J. Immunol. 163:1441. (IP, WB)
3. Onami TM, et al. 2002. J. Immunol. 168:6022.
4. van der Most RG, et al. 2003. Intl. Immunol. 15:119.
5. Chu VT, et al. 2007. J. Immunol. 179:5947.
6. Lang A, et al. 2008. J. Immunol. 180:4848. PubMed
7. Gibbert K, et al. 2010. J. Immunol. 185:6179. PubMed
Product Citations：
1. Barrett N, et al. 2016. Cell Rep. 16: 1039-1054. PubMed
2. Rubinstein M, et al. 2008. Blood. 112:3704. PubMed
3. Bánki Z, et al. 2010. PLoS One. 5:e1000891. PubMed
4. Kidder D, et al. 2013. J Immunol. 190:2593. PubMed
文献支持
抗小鼠 CD43 激活相关糖型 荧光标记FITC 抗体
￥3900
